Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Tulane researcher reports on origin of deadly fever outbreak

15.09.2006
Multiple genetic varients clue to source of Marburg hemorrhagic fever outbreak

Bats or other cave dwelling animals may have been responsible for the deadly 1998–2000 outbreak of Marburg hemorrhagic fever among gold miners in the Democratic Republic of the Congo, according to an article in the Aug. 31, 2006, issue of the New England Journal of Medicine.

Daniel G. Bausch, associate professor of Tropical Medicine at Tulane University School of Public Health and Tropical Medicine and an international team of researchers identified multiple genetic variants of the virus in the outbreak, meaning the fever may have been spread directly to humans by the host animals. Marburg hemorrhagic fever, a severe filovirus-caused disease related to Ebola, was first identified in European research facilities in 1967 after outbreaks traced to infected monkeys imported from Uganda. Only a few sporadic cases were reported until the 1998–2000 outbreak in the Democratic Republic of the Congo.

The team recorded a fatality rate of 83 percent for that outbreak. Young male miners comprised 52 percent of the cases, suggesting that exposure in underground mines was a factor in the spread of the disease. The discovery of multiple different genetic variants of the virus indicates that the two-year outbreak was fueled by repeated new introductions of the virus into humans from the primary reservoir, rather than simply a single introduction followed by person-to-person spread.

Bausch's study enhances our understanding of Marburg virus, which the Centers for Disease Control and Prevention list as a "select agent" that may potentially be used in bioterrorism. There is currently no approved treatment or vaccine for the disease.

Arthur Nead | EurekAlert!
Further information:
http://www.tulane.edu

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>