Changes in heart mass and volume linked to early signs of left ventricle problems
Using magnetic resonance imaging technology, or MRI, to tag the work of millions of individual strands of heart muscle fibers, researchers at Johns Hopkins have successfully mapped the smallest deformations inside the beating hearts of 441 middle-aged and elderly men and women who have either silently developed heart disease or remained healthy. The novel use of the MRI allowed the researchers to create a gridlike, three-dimensional, computer image of each heart and track gradual deformations during each heartbeat.
The Hopkins findings, published in last weeks edition of the journal Circulation, are believed to be the first to tie specific "remodeling" changes in heart mass and volume to early and growing signs of trouble in any specific region of the muscle, specifically, the anterior wall (or front part) of the left ventricle, the hearts main pumping chamber.
David March | EurekAlert!
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