A detectable decline in energy production by mitochondria — the organelles that are the cells furnace for energy production — seems to be a key problem leading to insulin resistance, and thus to type 2 diabetes, according to studies by Howard Hughes Medical Institute researchers.
The research team said that insulin resistance — an impaired response to the presence of insulin — is detectable as early as 20 years before the symptoms of diabetes become evident. In fact, insulin resistance is now seen as the best predictor that type 2 diabetes will eventually develop, said the studys senior author, Gerald I. Shulman, a Howard Hughes Medical Institute investigator at the Yale University School of Medicine.
In the new study examining how insulin interacts with the energy-producing mitochondria inside living cells, Shulman and his colleagues found that the rate of insulin-stimulated energy production by mitochondria is significantly reduced in the muscles of lean, healthy young adults who have already developed insulin resistance and who are at increased risk of developing diabetes later in life.
Jim Keeley | EurekAlert!
Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care
Disrupted fat breakdown in the brain makes mice dumb
19.05.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.
In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...
Dental plaque and the viscous brown slime in drainpipes are two familiar examples of bacterial biofilms. Removing such bacterial depositions from surfaces is...
23.05.2017 | Event News
22.05.2017 | Event News
17.05.2017 | Event News
23.05.2017 | Physics and Astronomy
23.05.2017 | Life Sciences
23.05.2017 | Event News