Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Older Americans with new-onset diabetes have high risk of pancreatic cancer

01.08.2005


In a groundbreaking population-based study, researchers in Mayo Clinic Cancer Center found that new onset of hyperglycemic diabetes in adults age 50 or older may be a signal of underlying pancreatic cancer. The risk of developing the cancer within three years after a new diagnosis of diabetes is eight times higher than for the average same-age individual. The findings will be published in the Aug. 1 issue of Gastroenterology.



"Pancreatic cancer is difficult to detect until it is in an advanced stage, leaving little hope for patients," says Suresh Chari, M.D., Mayo Clinic gastroenterologist and lead investigator of the study. "This study is important, because it leads us closer to finding indicators that will allow earlier detection and treatment."

Pancreatic cancer is a deadly disease – nearly all patients die – that claims 32,000 lives in the United States each year and has an equal number of diagnoses annually. Patients with this type of cancer seldom exhibit disease-specific symptoms until the cancer is at an advanced stage, and two major obstacles prevent physicians from making an early diagnosis. First is the lack of a high-risk group – a population of individuals, other than rare genetic disorders, in whom pancreatic cancer is common; and second is a lack of a PSA-like blood test for pancreatic cancer. Dr. Chari and his team’s study shows that new-onset diabetes defines a high-risk group for pancreatic cancer.


While the study showed that about 1 percent of patients who met fairly stringent criteria for diabetes developed pancreatic cancer within three years, in most patients the cancer was at an advanced stage at diagnosis. Because patients in this study had not been screened for diabetes or pancreatic cancer, Dr. Chari’s team was looking at those diagnosed after the fact. "Our goal now is to identify a marker in the blood that will enable us to distinguish diabetes associated with pancreatic cancer from the far more common type 2 diabetes," said Dr. Chari, "so we are able to screen patients with new-onset diabetes to detect pancreatic cancer before it spreads."

The study population of 2,122 patients was drawn from the Rochester Epidemiology Project and included all residents age 50 or older of Rochester, Minn., between 1950 and 1995. Comparison to the general populace was made using data from the Iowa Surveillance, Epidemiology and End Results (SEER) program.

Elizabeth Zimmermann | EurekAlert!
Further information:
http://www.mayo.edu

More articles from Health and Medicine:

nachricht Finnish research group discovers a new immune system regulator
23.02.2018 | University of Turku

nachricht Minimising risks of transplants
22.02.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Attoseconds break into atomic interior

A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.

In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...

Im Focus: Good vibrations feel the force

A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.

By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...

Im Focus: Developing reliable quantum computers

International research team makes important step on the path to solving certification problems

Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Basque researchers turn light upside down

23.02.2018 | Physics and Astronomy

Finnish research group discovers a new immune system regulator

23.02.2018 | Health and Medicine

Attoseconds break into atomic interior

23.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>