Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Older Americans with new-onset diabetes have high risk of pancreatic cancer

01.08.2005


In a groundbreaking population-based study, researchers in Mayo Clinic Cancer Center found that new onset of hyperglycemic diabetes in adults age 50 or older may be a signal of underlying pancreatic cancer. The risk of developing the cancer within three years after a new diagnosis of diabetes is eight times higher than for the average same-age individual. The findings will be published in the Aug. 1 issue of Gastroenterology.



"Pancreatic cancer is difficult to detect until it is in an advanced stage, leaving little hope for patients," says Suresh Chari, M.D., Mayo Clinic gastroenterologist and lead investigator of the study. "This study is important, because it leads us closer to finding indicators that will allow earlier detection and treatment."

Pancreatic cancer is a deadly disease – nearly all patients die – that claims 32,000 lives in the United States each year and has an equal number of diagnoses annually. Patients with this type of cancer seldom exhibit disease-specific symptoms until the cancer is at an advanced stage, and two major obstacles prevent physicians from making an early diagnosis. First is the lack of a high-risk group – a population of individuals, other than rare genetic disorders, in whom pancreatic cancer is common; and second is a lack of a PSA-like blood test for pancreatic cancer. Dr. Chari and his team’s study shows that new-onset diabetes defines a high-risk group for pancreatic cancer.


While the study showed that about 1 percent of patients who met fairly stringent criteria for diabetes developed pancreatic cancer within three years, in most patients the cancer was at an advanced stage at diagnosis. Because patients in this study had not been screened for diabetes or pancreatic cancer, Dr. Chari’s team was looking at those diagnosed after the fact. "Our goal now is to identify a marker in the blood that will enable us to distinguish diabetes associated with pancreatic cancer from the far more common type 2 diabetes," said Dr. Chari, "so we are able to screen patients with new-onset diabetes to detect pancreatic cancer before it spreads."

The study population of 2,122 patients was drawn from the Rochester Epidemiology Project and included all residents age 50 or older of Rochester, Minn., between 1950 and 1995. Comparison to the general populace was made using data from the Iowa Surveillance, Epidemiology and End Results (SEER) program.

Elizabeth Zimmermann | EurekAlert!
Further information:
http://www.mayo.edu

More articles from Health and Medicine:

nachricht Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University

nachricht Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Stingless bees have their nests protected by soldiers

24.02.2017 | Life Sciences

New risk factors for anxiety disorders

24.02.2017 | Life Sciences

MWC 2017: 5G Capital Berlin

24.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>