Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

One In Five Women Would Consider Breast Removal To Reduce Their Risk Of Cancer

14.06.2005


A new international survey – connected to a study taking place at the University of Dundee - reveals that around one in five women would consider having both breasts removed to help reduce their risk of developing breast cancer if told they were at an increased risk of developing the disease.



The survey asked over 1500 women from around the world what choices they would make if told they were at high risk of developing breast cancer. Of the UK women who were questioned, up to one in three said they would consider having a double mastectomy.

Breast cancer experts wanted to learn more about women’s attitudes to breast cancer worldwide as they take the first step in trying to prevent up to 80 per cent of hormone sensitive breast cancers. With nearly half the women saying they were concerned about developing breast cancer, the study highlights the need for all prevention options, particularly new ones, to be clearly explained. Women in the UK are particularly worried with around 60 per cent saying they are concerned about breast cancer.


When asked if they would consider taking part in a trial investigating a preventive treatment for breast cancer, around 50 per cent of the women said they would consider it. Around 45 per cent of the women in the survey said they would consider taking a daily tablet as a preventive step against breast cancer.

In the UK there are around 41,000 women diagnosed with breast cancer every year. Around 80 per cent of these are post-menopausal women.

Scientists based at the University of Dundee are involved in one of the first worldwide prevention trials, called IBIS-II1, which is investigating whether a drug already used to treat breast cancer may have the ability to prevent the disease.

This landmark trial involves postmenopausal, high risk women taking a once-a-day pill containing the drug anastrozole. Previous trials investigating this drug as a treatment for breast cancer have shown that it reduces the risk of developing cancer in the opposite breast by over 50 per cent2.

The female hormone, oestrogen, is known to be the most important cause of breast cancer in post-menopausal women and anastrozole works by stopping oestrogen being produced.

This is the first time the drug is being investigated as a preventive measure. Cancer Research UK scientists are looking for 6,000 women from around the world to take part in the trial.

“The IBIS-II study is extremely important for women with an increased risk of developing breast cancer” commented Professor Jack Cuzick, Cancer Research UK’s lead researcher on the trial. “It is vitally important that women come forward to participate in the trial. It could provide them with a valuable option in helping to control breast cancer. Many of us already take medications to prevent heart disease so just imagine the possibilities if, in the future, we could use a simple, once-a-day medication, to reduce the occurrence of breast cancer. For those women faced with the reality of being at high risk of developing breast cancer, this trial has the potential to change their lives.”

He adds: “With over 30,000 post-menopausal women being diagnosed with breast cancer in the UK every year, i t’s vital that we look for effective ways of preventing the disease.”

Dr Lesley Walker, Director of Cancer Information at Cancer Research UK, says: “It is extremely rare for women to undergo a double mastectomy for preventive reasons and as an option, it is most relevant to women with a very strong family history of breast cancer. The global launch of IBIS-II aims to provide women with a new, far less radical option for preventing breast cancer at a time when numbers of women being diagnosed with the disease and concern about it, is so high. Through trials like this, women and researchers are working together to help discover clear and safe options for helping to prevent breast cancer.”

Professor Alastair Thompson, Professor of Surgical Oncology at Ninewells Hospital and Medical School, is the local trial co-ordinator in Dundee. He said, “We urge all women who are concerned about breast cancer to speak with their doctor. Understanding your risk of developing breast cancer and knowing what options are available are essential for all women. We are asking those women who are eligible for the trial to come forward and help us to find a way to help prevent breast cancer.”

To be eligible to take part in the IBIS II programme, women must be post-menopausal, not taking HRT and have at least twice the normal risk of breast cancer – for example someone whose mother or sister had breast cancer before the age of 50, or who has two family members with the disease.

Post-menopausal women who are interested in taking part should contact research nurses Gillian Little and Mhairi Hawkes on 01382 633850.

Roddy Isles | alfa
Further information:
http://www.dundee.ac.uk
http://www.ibis-trials.org
http://www.cancerhelp.org.uk

More articles from Health and Medicine:

nachricht Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University

nachricht The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

Im Focus: Fraunhofer ISE Develops Highly Compact, High Frequency DC/DC Converter for Aviation

The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.

Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

UTSA study describes new minimally invasive device to treat cancer and other illnesses

02.12.2016 | Medical Engineering

Plasma-zapping process could yield trans fat-free soybean oil product

02.12.2016 | Agricultural and Forestry Science

What do Netflix, Google and planetary systems have in common?

02.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>