Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New £6m biocentre to revolutionise the production of safer medicines

15.03.2005


The University of Manchester has been awarded £6m to open a new biocentre which will revolutionise the way future medicines are produced – making them safer and more effective.



The Manchester Centre for Integrative Systems Biology (MCISB) will pioneer an entirely new approach to biology which will not only help pharmaceutical companies to develop better drugs, but potentially reduce the time it takes to develop them.

The centre will pioneer the development of new technologies in Systems Biology – a new approach to genomics which uses complex computational and mathematical analysis to advance on traditional methods.


Professor Douglas Kell, Director of the MCISB, said: “The last fifty years of molecular biology have failed to discover the existence of a substantial number of genes in some very well studied organisms, which has hindered the development of the most effective medicines.”

“Our aim is to develop the systems which will allow University scientists and pharmaceutical companies to understand how every gene in an organism works and reacts. This will provide them with the tools they need to develop safer and more effective medicines and will put Manchester on the map as one of the world centres for systems biology research.”

The £6m grant has been awarded by The Biotechnology and Biological Sciences Research Council (BBSRC) and will be used to develop new methods of computational and mathematical analysis, validating these methods by testing them in yeast. These methods will then be used to create generic computational models with the potential to allow pharmaceutical companies to perform virtual trials of any medicine on any living organism.

“48% of genes in yeast are very similar to genes in humans. If we can understand how drugs react with yeast we can predict their reactions in humans too. This will allow pharmaceutical companies to develop medicines more efficiently because they will know in advance how people are going respond to them,” says Professor Kell.

Professor Stephen Oliver, a senior member of the MCISB research team and a leading expert in the field of genomics and yeast research, said: “Systems biology will be a major trend in life sciences for at least the next decade and the award at this centre by the BBSRC puts Manchester in the vanguard of this movement.”

Simon Hunter | alfa
Further information:
http://www.manchester.ac.uk/press/title,18324,en.htm

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

Im Focus: Using graphene to create quantum bits

In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.

In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

Physicists discover mechanism behind granular capillary effect

24.05.2017 | Physics and Astronomy

Measured for the first time: Direction of light waves changed by quantum effect

24.05.2017 | Physics and Astronomy

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>