Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New research reinforces importance of aerobic health

27.01.2005


Research published in the current issue of Science magazine reinforces the belief that aerobic capacity is an important determinant in the continuum between health and disease.

"Our data clearly show that the some of the major health problems of today, namely obesity, hypertension, and insulin resistance, are strongly influenced by our genes," said Steven Swoap, associate professor of biology at Williams Colleges, a member of the research team. "Coupled with our current environment of physical inactivity and over-abundance of food, this "metabolic syndrome" will become the primary health issue of the 21st century"

The research paper is titled "Cardiovascular Risk Factors from Artificial Selection for Low Aerobic Capacity in Rats."



Along with researchers from the Norwegian University of Science and Technology; St. Olav’s Hospital in Trondhelm, Norway; the Medical College of Ohio; and the University of Michigan, Swoap examined rats that had been genetically selected for high or low proficiency in endurance running. "In humans, the strong statistical association between fitness and survival suggests a link between impaired oxygen metabolism and disease," the article reports. "[Indeed,] after 11 generations, rats with low aerobic capacity scored high on cardiovascular risk factors that constitute the metabolic syndrome."

Swoap’s research "supports the notion that impaired regulation of oxidative pathways in mitochondria may be a common factor liking reduced total-body aerobic capacity to cardiovascular and metabolic disease."

His research has been published in the American Journal of Physiology, the Journal of Experimental Biology and the Journal of Applied Physiology and is supported through multi-year grants from the National Institutes of Health (NIH) and the National Science Foundation (NSF). The NIH awarded him nearly $100,000 to determine why skeletal muscle becomes more fatigable after disuse, and the NSF has funded his research on the mechanism of how restricting caloric intake lowers blood pressure, with grants totaling more than $700,000.
In 2001, Swoap won the Arthur C. Guyton Award for Excellence in Integrative Physiology from the American Physiological Society, for demonstrating outstanding promise in his research program in physiology. He was also invited to give a lecture on "Molecular Biology in Skeletal Muscles" at the 2001 meeting of the New England American College of Sports Medicine and was the winner of the American College of Sports Medicine New Investigator Award in 2000.

Swoap is the chair of the biochemistry and molecular biology program at Williams College, where he has taught since 1996. His research has focused on the molecular bases of changes in muscle physiology, and how muscle fibers change as a result of exercise. In addition to courses on physiology, Swoap teaches the popular "Biology of Exercise and Nutrition" class, which attracted over 10 percent of the student body its first year offered.

He earned his B.S. in biology from Trinity University in 1990 and his Ph.D. in physiology and biophysics from the University of California at Irvine in 1994. He did post-doctoral work at the University of Texas Southwestern Medical Center in Dallas.

Science is published by the American Association for the Advancement of Science, an international non-profit organization with a mission to "advance science and serve society" through initiatives in science policy, international programs, science education and the publication of scientific newsletters, books and reports.

Jo Procter | EurekAlert!
Further information:
http://www.williams.edu

More articles from Health and Medicine:

nachricht Vanishing capillaries
23.03.2017 | Technische Universität München

nachricht How prenatal maternal infections may affect genetic factors in Autism spectrum disorder
22.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

When Air is in Short Supply - Shedding light on plant stress reactions when oxygen runs short

23.03.2017 | Life Sciences

Researchers use light to remotely control curvature of plastics

23.03.2017 | Power and Electrical Engineering

Sea ice extent sinks to record lows at both poles

23.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>