Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cardiovascular risk factors in midlife strongly linked to risk of dementia

25.01.2005


High cholesterol, hypertension, diabetes, and smoking have long been considered and treated as risk factors for cardiovascular disease. A new study has concluded that these same cardiovascular (CV) risk factors in middle age may also increase significantly the risk of dementia in old age. The study of nearly 9,000 northern Californians is published in the January 25 issue of Neurology, the scientific journal of the American Academy of Neurology.



Each of these four CV risk factors (diabetes, hypertension, high cholesterol, and smoking) identified at midlife (age 40 to 44) was associated with a 20 to 40 percent increased risk of dementia in later life. Compared to those with no risk factors, those with two of the risk factors were 70 percent (or .7 times) more likely to be diagnosed with dementia; those with three were more than twice as likely; while individuals unfortunate enough to have all four risk factors had a 237 percent (or 2.37 times) greater risk of being diagnosed with dementia.

Correspondingly, treating one’s risk factors for heart disease may also reduce the risk for dementia. Earlier treatment may have an even greater benefit by virtue of the cumulative effect of longer exposure to protective therapies.


By risk factor, those with diabetes were 46 percent more likely to develop dementia. Participants with high total cholesterol were 42 percent more likely. Those with hypertension (high blood pressure) were 24 percent more likely. Participants who reported ever smoking at midlife were 26 percent more likely to develop dementia. The effects of CV risk factors on prevalence of dementia were not significantly different among race or gender subgroups.

While previous studies have reported an association between individual CV risk factors and dementia, whether these risk factors in midlife are prospectively associated with risk of dementia in older age had not been thoroughly investigated.

"The real strength of our study is the large, multiethnic cohort of men and women, followed up for 27 years, all with equal access to medical care," said study author Rachel Whitmer, PhD, of Kaiser Permanente Division of Research in Oakland, Calif.

Marilee Reu | EurekAlert!
Further information:
http://www.aan.com

More articles from Health and Medicine:

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

nachricht ASU scientists develop new, rapid pipeline for antimicrobials
14.12.2017 | Arizona State University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

Im Focus: Successful Mechanical Testing of Nanowires

With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong

Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Plasmonic biosensors enable development of new easy-to-use health tests

14.12.2017 | Health and Medicine

New type of smart windows use liquid to switch from clear to reflective

14.12.2017 | Physics and Astronomy

BigH1 -- The key histone for male fertility

14.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>