Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cervical cancer treatment depends on patient age

29.12.2004


Elderly women with cervical cancer face double jeopardy. Not only does their advanced age decrease chances of survival, it also decreases the likelihood that they’ll be given the most aggressive treatments for their disease, according to a study by researchers at Washington University School of Medicine in St. Louis. The study is reported in the Jan. 1, 2005 issue of the journal Cancer.



"The aging of the U.S. population has increased interest in treatments for geriatric cancer patients, but there is very little data about treatment of cervical cancer in the elderly," says first author Jason Wright, M.D., a Washington University gynecological oncologist and part of a team of investigators associated with the Siteman Cancer Center.

A recent report issued by the National Cancer Institute showed that women ages 65 and older die from cervical cancer at a rate of 7.6 per 100,000, compared to 2.1 for women younger than 65.


The Washington University researchers analyzed medical records of more than 1,500 patients treated for invasive cervical cancer at Barnes-Jewish Hospital and the Siteman Cancer Center between 1986 and 2003. They divided the records into two categories, women younger than 70 and women 70 or older.

Their study showed that regardless of the stage of tumor development, elderly patients were likely to receive less aggressive treatment. Surgery was used to treat 16 percent of the elderly group, whereas 54 percent the younger patients underwent surgery. The remainder of the patients were treated with radiation without surgery.

For women treated with radiation therapy alone, the chances of surviving were five times lower than for those treated surgically. Elderly women treated with radiation were given lower doses on average, and they were nine times more likely to forego treatment altogether.

Treatment choices were not the only factors to affect survival; the stage of tumor advancement and the presence of other medical conditions also influenced outcomes. But, this study showed that advanced age itself, for as yet undefined reasons, was a factor that strongly affected survival, independent of the other factors. Women over 70 with cervical cancer had about 1.6 times the risk of death as did comparable women under 70 having the same tumor stage, type of treatment and additional medical diseases.

According to Wright, the effect of advanced age is an important consideration for physicians treating cervical cancer patients. "It may be that physicians are influenced by the presence of other medical conditions when choosing treatments for elderly patients," he says. "But, other studies have shown that elderly patients tolerate radiation therapy and aggressive surgical therapy well, so in light of the age-related risk from cancer, physicians should give greater thought to recommending aggressive treatment."

Next the researchers will study the effect of the presence of other medical conditions on the treatment of cervical cancer. They are also analyzing the type of treatments given to adolescents with abnormal pap smears.

Jim Dryden | EurekAlert!
Further information:
http://www.wustl.edu

More articles from Health and Medicine:

nachricht Millions through license revenues
27.04.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht New High-Performance Center Translational Medical Engineering
26.04.2017 | Fraunhofer ITEM

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

Bare bones: Making bones transparent

27.04.2017 | Life Sciences

Study offers new theoretical approach to describing non-equilibrium phase transitions

27.04.2017 | Physics and Astronomy

From volcano's slope, NASA instrument looks sky high and to the future

27.04.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>