Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Cervical cancer treatment depends on patient age


Elderly women with cervical cancer face double jeopardy. Not only does their advanced age decrease chances of survival, it also decreases the likelihood that they’ll be given the most aggressive treatments for their disease, according to a study by researchers at Washington University School of Medicine in St. Louis. The study is reported in the Jan. 1, 2005 issue of the journal Cancer.

"The aging of the U.S. population has increased interest in treatments for geriatric cancer patients, but there is very little data about treatment of cervical cancer in the elderly," says first author Jason Wright, M.D., a Washington University gynecological oncologist and part of a team of investigators associated with the Siteman Cancer Center.

A recent report issued by the National Cancer Institute showed that women ages 65 and older die from cervical cancer at a rate of 7.6 per 100,000, compared to 2.1 for women younger than 65.

The Washington University researchers analyzed medical records of more than 1,500 patients treated for invasive cervical cancer at Barnes-Jewish Hospital and the Siteman Cancer Center between 1986 and 2003. They divided the records into two categories, women younger than 70 and women 70 or older.

Their study showed that regardless of the stage of tumor development, elderly patients were likely to receive less aggressive treatment. Surgery was used to treat 16 percent of the elderly group, whereas 54 percent the younger patients underwent surgery. The remainder of the patients were treated with radiation without surgery.

For women treated with radiation therapy alone, the chances of surviving were five times lower than for those treated surgically. Elderly women treated with radiation were given lower doses on average, and they were nine times more likely to forego treatment altogether.

Treatment choices were not the only factors to affect survival; the stage of tumor advancement and the presence of other medical conditions also influenced outcomes. But, this study showed that advanced age itself, for as yet undefined reasons, was a factor that strongly affected survival, independent of the other factors. Women over 70 with cervical cancer had about 1.6 times the risk of death as did comparable women under 70 having the same tumor stage, type of treatment and additional medical diseases.

According to Wright, the effect of advanced age is an important consideration for physicians treating cervical cancer patients. "It may be that physicians are influenced by the presence of other medical conditions when choosing treatments for elderly patients," he says. "But, other studies have shown that elderly patients tolerate radiation therapy and aggressive surgical therapy well, so in light of the age-related risk from cancer, physicians should give greater thought to recommending aggressive treatment."

Next the researchers will study the effect of the presence of other medical conditions on the treatment of cervical cancer. They are also analyzing the type of treatments given to adolescents with abnormal pap smears.

Jim Dryden | EurekAlert!
Further information:

More articles from Health and Medicine:

nachricht Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg

nachricht New potential cancer treatment using microwaves to target deep tumors
12.10.2016 | University of Texas at Arlington

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>