A team of Danish researchers have discovered that by blocking a specific enzyme, it is possible to check the spread of cancer in the body. This finding may be the first step towards preventing deaths due to cancer spreading to other parts of the body. The discovery may also help reduce the amount of chemotherapy used.
The discovery, which was recently published in the prestigious International Journal of Cancer, was made by a research team from the Finsen Laboratory at Copenhagen University Hospital – Rigshospitalet and the Institute of Molecular Biology at the University of Copenhagen. “What is special about the enzyme – urokinase plasminogen activator (uPA) – is that the cancer needs the enzyme in order to spread throughout the body, but the body does not need the enzyme to function normally. This means that we should be able to block the enzyme and thereby check the spread of the cancer without causing the strong side effects for the patients that we see with other forms of therapy today,” says Morten Johnsen, Institute of Molecular Biology, University of Copenhagen.
“When women discover a lump in their breast, it can be removed. But if the cancer has spread to other parts of the body, such as the lungs, then it can become life-threatening. So we’ve come a long way towards being able to limit the spread of the cancer in the body,” says Kasper Almholt, PhD, Finsen Laboratory.
Associate Prof. Morten Johnsen | alfa
Millions through license revenues
27.04.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
New High-Performance Center Translational Medical Engineering
26.04.2017 | Fraunhofer ITEM
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Medical Engineering
28.04.2017 | Earth Sciences
28.04.2017 | Life Sciences