Evidence of exposure to a monkey virus possibly related to cancer has been found in the blood of North American zoo workers, according to a study in the December 15 issue of The Journal of Infectious Diseases, now available online. The virus, a polyomavirus known as simian virus 40 (SV40), has long been a subject of public health concern, in part because it has been shown to cause cancer in laboratory animals, and some investigators have reported SV40 DNA in human tumors.
The authors, Eric A. Engels and coworkers at the National Cancer Institute, National Institutes of Health, Rockville, MD, the Centers for Disease Control and Prevention, Atlanta, GA, and The Johns Hopkins University School of Medicine, Baltimore, MD, studied 254 zoo workers, 109 of whom handled primates extensively and the remainder not at all. An antibody assay showed that SV40 reactivity was more common among primate workers (23 percent) than among the other workers (10 percent). These low rates, which suggested absence of ongoing SV40 replication, contrasted with assay results showing 85 percent and 56 percent reactivity, respectively, for two other polyomaviruses, BK and JC, which are highly prevalent in humans and establish lifelong infection.
When the investigators used particles of SV40, BK, and JC to evaluate whether SV40-positive reactions were specific or represented cross-reacting antibody responses, only 14 of 29 subjects demonstrated specific reactivity. Engels and coworkers commented that this suggested that much of their SV40-positive results were probably due to BK or JC virus cross-reactivity.
Observing the cell's protein factories during self-assembly
15.06.2018 | Charité - Universitätsmedizin Berlin
Scientists unravel molecular mechanisms of Parkinson's disease
13.06.2018 | The Francis Crick Institute
Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.
Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...
The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.
Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.
An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.
Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...
Light detection and control lies at the heart of many modern device applications, such as smartphone cameras. Using graphene as a light-sensitive material for...
Water molecules exist in two different forms with almost identical physical properties. For the first time, researchers have succeeded in separating the two forms to show that they can exhibit different chemical reactivities. These results were reported by researchers from the University of Basel and their colleagues in Hamburg in the scientific journal Nature Communications.
From a chemical perspective, water is a molecule in which a single oxygen atom is linked to two hydrogen atoms. It is less well known that water exists in two...
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