McMaster researcher investigates why influenza epidemics happen in the winter
Flu season is on its way to homes across Canada. But the question of why influenza epidemics take place in the few cold months of winter remains unanswered. Is it the change in the weather? The return to school? Or increased viral production under winter conditions?
The answer to the increase of flu cases may be extremely minute seasonal changes, says David Earn of the Department of Mathematics & Statistics at McMaster University. Earn, who uses mathematical models to investigate and understand how infectious diseases move through populations, recently examined the question of why most people catch the flu in the winter.
Julia Thomson | EurekAlert!
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Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
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