Research has shown that the drug tamoxifen citrate not only helps prevent recurrence of breast cancer, but it also can keep the deadly disease from occurring in the first place in some women.
But a new University of North Carolina at Chapel Hill study indicates its unlikely that tamoxifen will ever be given widely to women to prevent breast cancer. Thats because the drug would avert only a maximum of 6 percent to 8.3 percent of breast tumors in eligible women, UNC School of Medicine researchers have found. "Our calculations showed that tamoxifens possibly harmful side effects, including blood clots and stroke, would rule out some 90 percent of women who might benefit from taking it each day," said Dr. Russell P Harris, associate professor of medicine at UNC. A report on the study appears in the latest issue of the Archives of Internal Medicine.
Besides Harris, a member of UNCs Lineberger Comprehensive Cancer Center, authors are principal investigator Dr. Carmen L. Lewis, assistant professor of medicine at UNC; Dr. Linda S. Kinsinger, assistant director of the VA Center for Health Promotion and Disease Prevention; and Robert J. Schwartz, a computer programmer at UNCs Cecil G. Sheps Center for Health Services Research.
David Williamson | EurekAlert!
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Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
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