Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Yoghurt won’t stop thrush

13.09.2004


Probiotics are not always the right approach.



Millions of women around the world have probably used yoghurt as a folk remedy to prevent thrush while taking antibiotics. A Melbourne GP and PhD student has proven that Lactobacillus acidophilus, a key bacterium in yoghurt, was not effective in the prevention of thrush (‘vulvovaginitis’) after antibiotics. Her findings were published recently in the eminent British Medical Journal (BMJ). “It’s a reminder that all medicines, even natural ones need to be tested,” says Dr Pirotta.

235 Melbourne women took probiotic (containing lactobacillus bacteria) or placebo preparations orally or vaginally until four days after completion of their antibiotic course. They recorded any symptoms and provided vaginal swabs for analysis. The results were so clear cut that the trial was cut short on ethical grounds.


Dr Pirotta was surprised by her results, given that the folk remedy was so popular with women, including her own patients. “But at least now women can be better informed and can choose to use effective treatments instead,” she said. “Currently, there are no recommended medicines to prevent thrush, so women should discuss their options with their health care providers.”

Around 50% of women will suffer a bout of thrush after antibiotics at least once in their lifetime. Although thrush usually does not kill people, it does have a big impact on women’s physical and emotional wellbeing, as well as on their relationships. In 1995 the costs associated with diagnosing and treating thrush in the United States were $US1.8 billion.

The clinical trial was instigated after Dr Pirotta’s earlier research that found that around 40% of women had used yoghurt or Lactobacillus to try to prevent or treat thrush after antibiotics.

These women also reported that they were concerned about getting thrush after antibiotics, and for a small number, the concern was so great that they would choose not to take the antibiotics. She also found that more than two thirds of GPs and pharmacists that she surveyed thought that oral yoghurt or Lactobacillus could be effective to prevent thrush after antibiotics and they had recommended this therapy to women when prescribing or dispensing antibiotics.

Dr Pirotta said that “complementary therapies probably have a lot to offer in health care. It was disappointing to find that this type of Lactobacillus was not effective in this case. But this is a reminder that all medicines, even ‘natural’ ones, need to be tested, and wherever possible, treatments should be based on evidence.”

“This simple and relatively inexpensive study will change how GPs advise women about thrush prevention,” says Professor Michael Kidd, President of the Royal Australian College of General Practitioners. “It demonstrates that research in general practice can help GPs deliver the best, most cost effective and evidence based care. We need to invest more in this kind of targeted medical research.”

Dr Pirotta was one of 15 early career scientists selected to take part in the 2004 Fresh Science progam held recently in Melbourne. The one who most meets the program requirements will win a study tour of the UK courtesy of the British Council Australia.

Niall Byrne | alfa
Further information:
http://www.freshscience.org

More articles from Health and Medicine:

nachricht A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital

nachricht Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

NASA's Fermi catches gamma-ray flashes from tropical storms

25.04.2017 | Physics and Astronomy

Researchers invent process to make sustainable rubber, plastics

25.04.2017 | Materials Sciences

Transfecting cells gently – the LZH presents a GNOME prototype at the Labvolution 2017

25.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>