Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Patients with COPD may be missing out on appropriate treatment because of incorrect or no diagnosis

07.09.2004


Patients with Chronic Obstructive Pulmonary Disease (COPD) are frequently misdiagnosed or remain undiagnosed, and may therefore be missing out on appropriate treatment, according to the results of a primary care study presented today at the annual European Respiratory Society (ERS) meeting in Glasgow, Scotland.1

COPD is a progressive respiratory disease that causes significant deterioration of lung function and chronic breathlessness that can lead to severe disability.2 Limited airflow associated with COPD leads to excess air being trapped in the lungs after a person has exhaled. This condition, known as "air trapping", is a primary cause of breathlessness, which often restricts a person’s ability to perform daily activities such as walking up stairs or taking a shower.3,4

Although COPD is the fourth leading cause of death worldwide, claiming 2.75 million lives annually,5 it is estimated that up to 75% of patients in Europe6 and 50% in the United States are undiagnosed.7 Results of the study presented today at the ERS congress showed that more than half of those affected with COPD may first be incorrectly diagnosed with asthma by their primary care physician.1



"The level of misdiagnosis and under diagnosis seen in this study is very concerning," said Professor David Price, Chair of Primary Care, Respiratory, University of Aberdeen, UK, and principal study investigator. "Although recent guidelines for COPD emphasise the importance of accurate diagnosis, this has been challenging in primary care. There has been varied evidence for COPD signs and symptoms, and insufficient tools to make an accurate diagnosis. As a result, patients are suffering unnecessarily because they’re not receiving appropriate treatment."

The study presented at ERS enrolled 597 patients recruited from primary care practices in the UK and US aged 40 years or older with prior diagnoses or medications consistent with obstructive lung disease, but not previously diagnosed with COPD.1 Patients were given a study diagnosis based on spirometry.

Approximately 40% of patients in the study were found to have COPD.1 Of these:

51.5% reported a prior diagnosis of asthma only1
10.6% reported no prior diagnosis of obstructive lung disease1
37.9% reported a prior diagnosis of COPD component diseases (chronic bronchitis or emphysema).1

Among those COPD sufferers originally misdiagnosed with asthma, or with no prior diagnosis of obstructive lung disease, only 3.5% were receiving anticholinergic treatments,1 which together with beta-agonists are central to the symptomatic management of COPD.8

"It’s time for primary care professionals to re-think their approach to COPD to ensure patients receive an early, correct diagnosis and appropriate, effective treatment. Early intervention with smoking cessation therapy may slow disease progression, and appropriate medical therapy may slow the deterioration in patient quality of life seen with COPD," Professor Price said.

Additional study results presented at ERS showed that diagnosis of COPD in ’at risk’ groups (smokers and ex-smokers over 40 years of age) could be vastly improved if patients were asked a few symptom-based diagnostic questions to assess their lung health.9 If these questions were used for screening purposes in a primary care practice setting, testing 1000 people at high risk would lead to 297 spirometric examinations and 110 new diagnoses of COPD.9

"This simple questionnaire promises to be a cost-effective means of improving diagnosis rates, and thus appropriate management of one of the most common, debilitating and costly conditions seen in primary care," Professor Price said.

Patrick Ward | EurekAlert!
Further information:
http://www.shirehealthinternational.com

More articles from Health and Medicine:

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

nachricht Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Impacts of mass coral die-off on Indian Ocean reefs revealed

21.02.2017 | Earth Sciences

Novel breast tomosynthesis technique reduces screening recall rate

21.02.2017 | Medical Engineering

Use your Voice – and Smart Homes will “LISTEN”

21.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>