Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Alcohol Helps Reduce Damage After Heart Attack

01.09.2004


For years researchers have tried to determine why the French have such a lower rate of cardiovascular disease, given the amount of fat consumed in their diets. Red wine has been identified as one of the suspects in maintaining a healthy heart, but now a University of Missouri-Columbia researcher has found that alcohol, in moderation, from any source not only maintains a healthy heart, but can reduce the damage to affected tissue following a heart attack.



When a heart attack occurs, blood flow is reduced to several areas of the body. When the blood flow is restored, several processes take place in the body that actually cause more harm to the damaged tissue. When the blood supply is reestablished, the blood carries white blood cells to the areas damaged by the reduction in blood delivery. Unfortunately, these blood cells act like miniature hand grenades as they stick to the walls of the arteries and release toxic chemicals into the damaged tissues, causing additional cell death.

“Following a heart attack, physicians try to establish reperfusion, or normalize the blood flow in the body,” said Ron Korthuis, distinguished professor and chair of medical pharmacology and physiology. “The damaged tissues begin releasing a variety of molecules that attract the white blood cells to the damaged areas. When the white blood cells arrive, they attach to the adhesion molecules on the blood vessel walls and then start destroying the damaged tissue. One type of adhesion molecule that is affected by the alcohol ingestion is P-selectin”


P-selectins make the artery walls sticky enough that the white blood cells will attach when they are in the affected areas. Using an animal model, Korthuis found that when alcohol was introduced to the system at a rate of one drink every 48 hours, the alcohol would trigger a chemical reaction in the body that would make the artery walls slick and stop the white blood cells from attaching to the damaged tissue. In subjects that were treated with the alcohol, the tissue affected by the low blood flow was much healthier and stronger than the untreated tissue. However, Korthuis warns that this is not a license to drink.

“Every time you take a drink of alcohol, you’re killing brain cells,” Korthuis said. “We’re trying to identify these chemical reactions so that we can develop a drug that would start this chain reaction, but not have the side effects of alcohol. We’ve also found other natural compounds have similar effects such as capsaicin, a compound in Tabasco sauce that creates that hot sensation.”

Korthuis’ research will be published this fall in Microcirculation. He also has been published in the American Journal of Physiology and Free Radicals Biology and Medicine on similar research studies.

| newswise
Further information:
http://www.missouri.edu

More articles from Health and Medicine:

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

nachricht The gut microbiota plays a key role in treatment with classic diabetes medication
01.06.2017 | University of Gothenburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Quantum thermometer or optical refrigerator?

23.06.2017 | Physics and Astronomy

A 100-year-old physics problem has been solved at EPFL

23.06.2017 | Physics and Astronomy

Equipping form with function

23.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>