Body tissues such as blood vessels, cartilage and skin—even whole organs such as kidneys, livers and hearts—could become more widely available for transplants as a result of a patent issued recently to Organ Recovery Systems of Chicago for a method to chill body tissues and organs well below freezing without forming ice crystals. The new process for tissue "vitrification"—-chilling tissue and organs to a disordered, glass-like solid without ice formation—-was developed with support from the National Institute of Standards and Technology (NIST) Advanced Technology Program and the National Institutes of Health.
There is an urgent need for tissues and organs for transplantation. Doctors conducted over 24,000 organ transplants in the United States in 2002; yet someone is added to the donor waiting list every 12 minutes and 16 people die each day waiting for an organ transplant. A significant roadblock to the broader use of transplantation, regardless of the source (donated human, cross-species or artificial), has been the problem of preserving the transplant tissue. Better preservation techniques would allow transplant materials to be shipped anywhere in the world or, better yet, collected and stored in something akin to blood banks until needed.
Organs and some tissues are presently stored for short periods at refrigerator temperatures (approximately 4 °C) and freezing has not been possible due to ice crystals, which damage delicate cells and greatly reduce the viability or functions of the tissue. Chemicals called cryoprotectants reduce ice formation but have toxic effects that introduce their own problems. The Organ Recovery Systems technique combines a mixture of cryoprotectant compounds that cancel each other’s toxicity and careful control of the cooling and warming processes to minimize damage to the tissue. The technique is discussed in U.S. patent no. 6,740,484. (Patent text available at www.uspto.gov.)
Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin
Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care
The world's highest gain high power laser amplifier - by many orders of magnitude - has been developed in research led at the University of Strathclyde.
The researchers demonstrated the feasibility of using plasma to amplify short laser pulses of picojoule-level energy up to 100 millijoules, which is a 'gain'...
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
24.05.2017 | Event News
23.05.2017 | Event News
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29.05.2017 | Earth Sciences
29.05.2017 | Life Sciences
29.05.2017 | Physics and Astronomy