Body tissues such as blood vessels, cartilage and skin—even whole organs such as kidneys, livers and hearts—could become more widely available for transplants as a result of a patent issued recently to Organ Recovery Systems of Chicago for a method to chill body tissues and organs well below freezing without forming ice crystals. The new process for tissue "vitrification"—-chilling tissue and organs to a disordered, glass-like solid without ice formation—-was developed with support from the National Institute of Standards and Technology (NIST) Advanced Technology Program and the National Institutes of Health.
There is an urgent need for tissues and organs for transplantation. Doctors conducted over 24,000 organ transplants in the United States in 2002; yet someone is added to the donor waiting list every 12 minutes and 16 people die each day waiting for an organ transplant. A significant roadblock to the broader use of transplantation, regardless of the source (donated human, cross-species or artificial), has been the problem of preserving the transplant tissue. Better preservation techniques would allow transplant materials to be shipped anywhere in the world or, better yet, collected and stored in something akin to blood banks until needed.
Organs and some tissues are presently stored for short periods at refrigerator temperatures (approximately 4 °C) and freezing has not been possible due to ice crystals, which damage delicate cells and greatly reduce the viability or functions of the tissue. Chemicals called cryoprotectants reduce ice formation but have toxic effects that introduce their own problems. The Organ Recovery Systems technique combines a mixture of cryoprotectant compounds that cancel each other’s toxicity and careful control of the cooling and warming processes to minimize damage to the tissue. The technique is discussed in U.S. patent no. 6,740,484. (Patent text available at www.uspto.gov.)
Scientists develop tiny tooth-mounted sensors that can track what you eat
22.03.2018 | Tufts University
NIH scientists describe potential antibody treatment for multidrug-resistant K. pneumoniae
14.03.2018 | NIH/National Institute of Allergy and Infectious Diseases
An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.
The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...
In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.
Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...
Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...
A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...
For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...
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22.03.2018 | Earth Sciences
22.03.2018 | Earth Sciences