Discovery aims to protect hospitalized patients
A team of international researchers has shown that coating implanted medical devices with a key peptide known as RIP can prevent the occurrence of bacterial colonization, biofilm formation and consequent drug-resistant Staphylococcus aureus infection - a leading cause of illness and death among hospitalized patients. RIP acts by preventing bacterial cell-to-cell communication, a process known as ’quorum sensing’. This is the first direct demonstration that inhibiting cell-to-cell communication can prevent staphylococcal infections. The discovery is reported in the June 24 on-line version of the Journal of Infectious Diseases, and will be reprinted in the journal’s July 15 hard-copy edition.
Staphylococcus aureus causes infections ranging from minor skin abscesses to life-threatening conditions, including pneumonia, meningitis, bone and joint infections (arthritis) and infections of the heart and bloodstream (endocarditis, septicemia, and toxic shock syndrome). Staph. infections are often associated with commonly used implanted medical devices, such as prostheses, catheters and artificial heart valves. Such infections can become tenacious because they are increasingly resistant to antibiotics, rendering them potent causes of illness and death.
Barbara Donato | EurekAlert!
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The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
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