Antibiotics, antihistamines, alcohol use, tobacco use, untreated hypertension and multisystem autoimmune diseases are potential risk factors for a retinal disorder known as central serous chorioretinopathy. This is the conclusion of a study appearing in the February issue of Ophthalmology, the clinical journal of the American Academy of Ophthalmology, the Eye M.D. Association. Central serous chorioretinopathy, or CSCR, is a disorder in which retinal cells detach and atrophy, causing visual impairment and loss.
In this case-control study, the records of 312 patients with CSCR and 312 patients with other ophthalmic conditions were examined at Boston University School of Medicines Department of Ophthalmology Hospitals and Clinics, the Massachusetts Eye and Ear Infirmary, the Department of Ophthalmology at Indiana University School of Medicine, and the offices of Ophthalmic Consultants of Boston.
Similar to previous studies, this study found the strongest association of CSCR with systemic corticosteroid use and pregnancy. Sean Koh, MD, a vitreoretinal fellow in the Retina Service of the Massachusetts Eye and Ear Infirmary, Harvard Medical School, and a co-author of the study, said, "In addition, this study shows a wide variety of new systemic factors are associated with CSCR. These are: alcohol, antibiotic, antihistamine and tobacco use, and untreated hypertension and allergic respiratory disease. Patients should be checked for these conditions, and advised to manage hypertension with anti-hypertensive medication, to cease use of alcohol and tobacco, and to avoid unnecessary or excessive use of antibiotics and antihistamines."
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