The omission of radiotherapy after breast-conserving surgery for early-stage breast cancer is associated with higher rates of relapse and a slightly higher mortality rate, according to a study in the January 21 issue of the Journal of the National Cancer Institute.
Many studies have shown that women with early-stage breast cancer who have breast-conserving surgery followed by radiotherapy have similar survival rates as women who have a mastectomy, and those women are also spared the disfiguration of losing their breast. However, radiotherapy prolongs the length of time that women are treated for breast cancer, the treatment can be costly, radiotherapy facilities are not common in all areas, and there are some side effects to radiotherapy.
For these reasons, several studies have examined the consequences of omitting radiotherapy from the treatment regimen. Vincent Vinh-Hung, M.D., of the Oncology Center at Academic Hospital in Jette, Belgium, and colleagues performed a pooled analysis of 15 randomized clinical trials of women with early-stage breast cancer who underwent breast-conserving surgery alone or surgery followed by radiotherapy. They analyzed recurrence rates based on information from 9,422 women, and mortality information was available for 8,206 women.
Katherine Arnold | EurekAlert!
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Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
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Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
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Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
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In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
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