Laboratory researchers and urologic oncologists from Fox Chase Cancer Center have demonstrated the ability to identify kidney cancer, including localized (stage I) cancer, in the urine of affected patients. The research, supported in part by a grant from the Flight Attendants Medical Research Institute and the National Cancer Institutes Early Detection Research Network, is published in the Dec. 15 issue of the journal Cancer Research.
As with other cancers, an early diagnosis of kidney cancer can result in curative treatment whereas the prognosis for advanced kidney cancer is poor. The challenge in diagnosing cancer early is developing an inexpensive, noninvasive, accurate and simple screening test.
The researchers say a urine test meets these standards. Currently, kidney cancer is diagnosed after radiographic imaging of the kidney, which may include an ultrasound, CT scan and/or MRI. Biopsy of a kidney mass is often difficult to interpret or may give a false negative result and therefore currently confirmation of radiographic results is primarily after surgical excision. There is no protein marker test for kidney cancer as there is for prostate cancer with the PSA test.
Karen Carter Mallet | EurekAlert!
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