Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Adult stem cell research

19.09.2003


Piero Anversa, M.D., director of the Cardiovascular Research Institute at New York Medical College, has demonstrated again that the heart has its own adult stem cells for regenerating heart muscle tissue following a coronary event. The research paper published in the September 19, 2003, issue of the journal Cell builds upon a study that appeared weeks ago in the September 2 Proceedings of the National Academy of Sciences.



The Cell study was conducted in Dr. Anversa’s laboratory by a team led by Dr. Anversa, Bernardo Nadal-Ginard, M.D., Ph.D., Annarosa Leri, M.D., and Jan Kajstura, Ph.D. "Until recently, the accepted paradigm in cardiac biology considered the adult mammalian heart a post-mitotic organ without regenerative capacity…that from shortly after birth to adulthood and senescence the heart has a relatively stable but slowly diminishing number of myocytes [heart muscle cells]…Evidence challenging the accepted wisdom has been slowly accumulating," they wrote.

Dr. Anversa’s investigation of heart failure has produced mounting evidence the heart can repair itself, debunking the notion that stem cells can be isolated only from adult tissues such as blood, skin, central nervous system, liver, gastrointestinal tract and skeletal muscle. In the current Cell paper, he and his colleagues utilized special cells isolated from adult rat hearts that have all the properties of cardiac progenitor cells. They injected an enriched mixture of the cells into ischemic hearts, where they gave rise to new myocytes as well as smooth muscle and endothelial cells that were structurally and functionally competent.


"We have already identified where the stem cells reside and are developing strategies to mobilize them to migrate to the damaged cardiac site…In time we will be developing Phase I clinical trial protocols for submission to the FDA," Dr. Anversa advises.

Donna E. Moriarty | EurekAlert!
Further information:
http://www.nymc.edu/

More articles from Health and Medicine:

nachricht 'Exciting' discovery on path to develop new type of vaccine to treat global viruses
18.09.2017 | University of Southampton

nachricht A new approach to high insulin levels
18.09.2017 | Schweizerischer Nationalfonds SNF

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

Im Focus: Fast, convenient & standardized: New lab innovation for automated tissue engineering & drug

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...

Im Focus: Silencing bacteria

HZI researchers pave the way for new agents that render hospital pathogens mute

Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...

Im Focus: Artificial Enzymes for Hydrogen Conversion

Scientists from the MPI for Chemical Energy Conversion report in the first issue of the new journal JOULE.

Cell Press has just released the first issue of Joule, a new journal dedicated to sustainable energy research. In this issue James Birrell, Olaf Rüdiger,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

New quantum phenomena in graphene superlattices

19.09.2017 | Physics and Astronomy

A simple additive to improve film quality

19.09.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>