Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Some forms of cancer behave in an unexpected way

16.09.2003


Tumor size may not be an accurate method of predicting lymph node involvement and disease progression in some breast cancers, according to investigators at the Research Institute of the McGill University Health Centre (MUHC). Their findings show that some types of breast tumors do not "play by the rules" and possibly, are more dangerous than previously believed.

"We have identified a group of breast cancer tumors that don’t conform to previous observations made in the general population of women with breast cancer," says MUHC geneticist and lead investigator, Dr. William Foulkes. "For these tumors there is only a very weak correlation between tumor size, the local spread of cancer cells and the likely severity of disease."

An associate professor in the Departments of Medicine, Human Genetics and Oncology at McGill University, Foulkes and his colleagues studied over 1500 women with breast cancer. Women with breast cancer who also had a mutation in particular gene, BRCA1, had unusual tumors. These tumors did not behave as expected - there was no clear correlation between tumor size and associated cancer in the axillary lymph nodes. This was not true for breast cancers in the general population, or those related to another breast cancer susceptibility gene, known as BRCA2.



These results are surprising, because previous studies have indicated that BRCA1-related breast cancers tend to behave aggressively. Thus, the preferred route of spread of BRCA1-related breast cancers may be different from other types of breast cancer. According to Foulkes, these observations have important implications for early diagnosis and treatment of women who carry this gene.

Christine Zeindler | McGill University
Further information:
http://www.mcgill.ca/
http://www3.interscience.wiley.com/cgi-bin/jissue/104532863

More articles from Health and Medicine:

nachricht Correct connections are crucial
26.06.2017 | Charité - Universitätsmedizin Berlin

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Collapse of the European ice sheet caused chaos

27.06.2017 | Earth Sciences

NASA sees quick development of Hurricane Dora

27.06.2017 | Earth Sciences

New method to rapidly map the 'social networks' of proteins

27.06.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>