Data from a five-year study suggests that limited-field radiation therapy (radiation directed at the tumor site) may be as effective as whole-breast radiation therapy in preventing breast cancer recurrence in women treated with breast-conserving surgery. The study appears in the August 20 issue of the Journal of the National Cancer Institute.
Whole-breast radiation therapy is part of standard treatment for women with early-stage breast cancer who have undergone breast-conserving surgery. However, it has never been clear how much tissue surrounding the tumor bed needs to be irradiated, and whole-breast radiation therapy has been associated with both acute and chronic toxicity. Researchers are now looking at whether limited-field radiation therapy could be a better option for patients at low risk for recurrence.
Frank A. Vicini, M.D., of the William Beaumont Hospital in Royal Oak, Mich., and his colleagues compared rates of local recurrence between 199 women treated with limited-field radiation therapy and 199 matched control women treated with whole-breast radiation therapy. All of the women had early-stage breast cancer and were treated with breast-conserving surgery; women were matched by age, tumor size, lymph-node status, margins of excision, estrogen receptor status, and use of adjuvant tamoxifen therapy.
Linda Wang | EurekAlert!
Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena
Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
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