Human papillomavirus 16 (HPV16), the virus responsible for approximately half of all cervical cancers, appears to be better at dodging the immune system than other HPV types, according to a large study of HIV-positive women in the July 16 issue of the Journal of the National Cancer Institute. The findings may help explain why HPV16 plays such a major role in causing cervical cancer in the general population.
Whereas other HPV types have a lower prevalence and incidence among women with stronger immune systems (in theory, the stronger the immune system, the better it is at fighting off infections), researchers detected similar levels of HPV16 in women with both weak and strong immune systems.
More than 30 types of HPV are known to infect the genital epithelium. HPV16 has been the strain most strongly associated with cervical cancer and its precursor lesions. What sets HPV16 apart from other HPV types has not been clear. A preliminary analysis of a study on HPV infection among women positive for HIV, the virus that causes AIDS, suggested that HPV16 may be less associated with immune status than other HPV types.
Linda Wang | EurekAlert!
Laser activated gold pyramids could deliver drugs, DNA into cells without harm
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What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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