Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

First West Coast baby born using frozen egg technique

11.07.2003


The University Fertility Consultants at the Oregon Health & Science University have successfully frozen human eggs that have resulted in the birth of a baby boy to a Forest Grove couple. It is the first successful birth using this method on the West Coast, according to David Battaglia, Ph.D., who utilized a technique that was developed in Bologna, Italy. He is also an associate professor of obstetrics and gynecology. Egg freezing technology is just emerging as a viable option for patients and this birth is one of about 25 such births in the United States and one of about 130 worldwide.


Adrian Alexander Pearson



This medical miracle came about as a result of an acute medical emergency.

The couple, Jennifer, 34, and Brian Pearson, 37, really had no other choice at the time. For nine years they had tried several fertility procedures in their effort to have a baby of their own. Jennifer was going through in vitro fertilization. In this technique a woman is given hormone injections to increase egg production. The eggs then must be retrieved on a set day, usually just before a woman’s body might start to release the eggs in ovulation. The eggs are fertilized in the lab with the partner’s sperm, and then the embryos are transferred after three to five days to the woman’s uterus.


March 28, 2002, was the day set for Jennifer’s egg retrieval. It was also the day her husband was in an intensive care unit with a ruptured appendix. Sperm collection for the in vitro fertilization was not possible. Jennifer and Brian’s hopes for a baby were temporarily dashed.

Two OHSU experts thought otherwise. After Battaglia consulted with Phillip Patton, M.D., who is also at University Fertility Consultants, offered to freeze Jennifer’s eggs using a new method. He had never done this clinically, but he had been keeping up with the successful protocol for egg cryopreservation developed by Eleonora Porcu, M.D., at the University of Bologna in Italy, the leader in this technique.

"I thought this might work," Battaglia said. They really had no other choice because unfertilized eggs don’t survive very long. It was devastating for them. She was watching all this fall apart. They had invested a lot of money -- and emotions."

Early that March afternoon they froze all the eggs they extracted. In late June Jennifer’s cycle was synchronized to receive the embryos. The eggs were thawed and the surviving eggs were fertilized using intracytoplasmic sperm injection. Two of the resulting embryos were transferred into Jennifer’s uterus, resulting in a single pregnancy.

Adrian Alexander Pearson, was born March 22, 2003. He weighed in at 9 pounds, 2 ounces, 21 inches long, and with a head of red hair.

"We’re so excited, Jennifer said. "Adrian’s very healthy. I tell people how special this baby is. My mother says to him, ’We prayed you all the way from heaven,’"

Added Brian: "We want people to know that miracles still exist."

Jennifer is a program manager at Intel, and her husband is a stay-at-home dad.

Embryos and sperm have been successfully frozen for years, but egg cryopreservation is more difficult because the technique had not been refined enough, Battaglia said. He used a newer technique developed by Porcu that has dramatically improved egg survival after freezing. In addition, Battaglia used an established technique to fertilize the eggs known as intracytoplasmic sperm injection (ICSI) in which a single sperm is injected into the egg cytoplasm, which dramatically improves fertilization rates with frozen eggs.

Battaglia will now develop a study protocol to prove that this can be accomplished again. Egg freezing has tremendous potential for certain women including younger women who want to wait to have a baby later in life, women about to undergo chemotherapy whose fertility may be affected, and women who want to donate eggs. And, of course, for a couple similar to the Pearsons who find that something goes wrong on the right day.

Christine Decker | EurekAlert!
Further information:
http://www.ohsu.edu/news/

More articles from Health and Medicine:

nachricht Hot cars can hit deadly temperatures in as little as one hour
24.05.2018 | Arizona State University

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>