Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Cardiac surgeons prove decreased mortality with off-pump coronary artery bypass grafting


(Landmark study on lowering the risk of CABG in high-risk patients reported at the American Association for Thoracic Surgery meeting)

NYU Medical Center’s cardiac surgeons Eugene Grossi, MD, and Aubrey Galloway, MD, announced new study findings demonstrating significantly lowered mortality, stroke, and overall risk of complications using off-pump coronary artery by-pass grafting (OPCAB) in high-risk patients. The findings were presented today during the Adult Cardiac Surgery Scientific Session at the 83rd annual meeting of the American Association of Thoracic Surgeons (AATS) meeting in Boston, MA.

One of the most exciting, and albeit controversial, innovations in coronary artery bypass grafting (CABG) over the past five years has been the introduction of “beating heart” or “off-pump” surgery. During this approach certain areas of the heart are immobilized with cardiac stabilizers allowing the heart to continue beating during surgery instead of placing the patient on conventional cardiopulmonary bypass (CPB).

NYU’s cardiac surgical research team conducted this study over 10 years to access the efficacy of off-pump coronary artery bypass versus conventional techniques in high-risk patients with severe aortic atherosclerotic disease.

According to Galloway, Director of Cardiac Surgical Research and co-investigator, “This is a very positive study for cardiac surgeons and their patients. Today, we are being asked to treat more patients who are older and have more co-existing conditions than patients a few years ago. Cardiac surgery has evolved to address this changing trend, and coronary artery bypass can now be done in a less traumatic way, minimizing risk in these older, more severely diseased patients.”

Outcomes data were collected on 5,737 CABG patients, identifying 913 patients as high-risk from advanced aortic atherosclerosis, using intraoperative transesophageal echocardiography. Of the high-risk patients, 235 underwent OPCAB, and a propensity case match analysis was conducted comparing data on 229 high-risk OPCAB patients with 229 high-risk conventional CPB patients. Results demonstrated a lower hospital mortality (6.5% vs 11.4%), lower risk of stroke (1.6% vs 5.7%) and better freedom from all complications (92.2% vs 80. 0%) in the OPCAB patients. Hospital stay was also 2 days shorter in the OPCAB patients.

“Despite recent advances in angioplasty and stenting, coronary artery bypass surgery is still necessary for hundreds of thousands of patients a year and this study demonstrates an approach for making the surgery safer in elderly, high-risk patients,” says Grossi, principal investigator of the study.

NYU’s cardiac surgical program is internationally recognized for both clinical care and innovative research. This study shows the risk-lowering benefits of newer techniques and evolving technologies in patients requiring coronary artery bypass grafting.

Deborah Coble | EurekAlert!
Further information:

More articles from Health and Medicine:

nachricht NIH scientists describe potential antibody treatment for multidrug-resistant K. pneumoniae
14.03.2018 | NIH/National Institute of Allergy and Infectious Diseases

nachricht Researchers identify key step in viral replication
13.03.2018 | University of Pittsburgh Schools of the Health Sciences

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Researchers at Fraunhofer monitor re-entry of Chinese space station Tiangong-1

In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.

Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...

Im Focus: Alliance „OLED Licht Forum“ – Key partner for OLED lighting solutions

Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.

They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...

Im Focus: Mars' oceans formed early, possibly aided by massive volcanic eruptions

Oceans formed before Tharsis and evolved together, shaping climate history of Mars

A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...

Im Focus: Tiny implants for cells are functional in vivo

For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.

In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...

Im Focus: Locomotion control with photopigments

Researchers from Göttingen University discover additional function of opsins

Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...

All Focus news of the innovation-report >>>



Industry & Economy
Event News

Virtual reality conference comes to Reutlingen

19.03.2018 | Event News

Ultrafast Wireless and Chip Design at the DATE Conference in Dresden

16.03.2018 | Event News

International Tinnitus Conference of the Tinnitus Research Initiative in Regensburg

13.03.2018 | Event News

Latest News

TRAPPIST-1 planets provide clues to the nature of habitable worlds

21.03.2018 | Physics and Astronomy

The search for dark matter widens

21.03.2018 | Materials Sciences

Natural enemies reduce pesticide use

21.03.2018 | Life Sciences

Science & Research
Overview of more VideoLinks >>>