The lack of a special protein crucial to cell growth and development may help cancer cells proliferate, new research suggests.
Cells without this protein – E2F3 – are usually rendered genetically unstable. In most cases, such instability would either kill a cell or keep it from growing. Yet sometimes mutations alter cells in such a way that they are able to thrive and multiply, creating tumors.
“In cancer, the absence or loss of E2F3 may be a double-edged sword,” said Gustavo Leone, the study’s lead author and an assistant professor in the Human Cancer Genetics Program at Ohio State University’s Comprehensive Cancer Center. “In most cases, the absence of E2F3 slows cell division. But the genetic instability created by the missing protein could instead increase the potential that a mutated cell would divide, and the resulting mutated cells could spread throughout the body.
Holly Wagner | EurekAlert!
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The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
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With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
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