Mayo Clinic researchers have proven for the first time that cells produced by the bone marrow can form new heart-muscle cells in adults, providing an important boost to research that could enable the body to replace heart muscle damaged by heart attack. The findings are now available online and will be published tomorrow in Circulation: Journal of the American Heart Association.
"Until recently, the heart has been seen as an organ that cannot be healed," says Noel Caplice, M.D., the Mayo Clinic cardiologist who led the study. "Heart-attack damage to the myocardium, or heart muscle, was considered irreversible. This study points the way to a process that could lead to heart repair."
The researchers studied four female patients with leukemia who had survived 35 to 600 days after receiving bone-marrow transplants from male donors. Heart tissue samples were examined at autopsy using special staining techniques, which showed that a small portion of the heart-muscle cells, or cardiomyocytes, contained male genetic material and had therefore originated from the donor marrow. Of the more than 80,000 cell nuclei examined, about 1 in 425 (.23 percent) contained the y chromosome.
Lee Aase | EurekAlert!
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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