Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Totality of evidence shows aspirin reduces risk of a first heart attack by one-third

18.11.2002


Aspirin conclusively reduces the risk of a first heart attack by 32%, according to a new report by researchers at Mount Sinai Medical Center & Miami Heart Institute. The findings were presented today at the American Heart Association’s Scientific Sessions in Chicago.



Charles H. Hennekens, MD, co-director of Cardiovascular Research, published the first randomized trial of aspirin in primary prevention. Under his direction, Rachel S. Eidelman, MD, a cardiology fellow, performed a detailed meta-analysis of the five randomized trials evaluating aspirin in the primary prevention of a first heart attack. The data conclusively demonstrate that aspirin significantly reduces the risk of a first heart attack by 32% as well as the combined risk of heart attack, stroke and vascular death by 15%.

These findings strongly support the recent guidelines from the American Heart Association (AHA) that aspirin should be recommended for all men and women whose 10-year risks of a first coronary event are 10% or greater. The U.S. Preventive Services Task Force released a similar position earlier this year, urging all physicians to speak about aspirin therapy with patients who have a 6% or greater 10-year risk of a coronary event.


"The individual trials and their meta-analysis strongly support the recent AHA recommendation," noted Dr. Hennekens. "The more widespread and appropriate use of aspirin in primary prevention could avoid more than 160,000 heart attacks and many other vascular events each year."

In 1988, Dr. Hennekens published the landmark Physicians’ Health Study (PHS) findings. The PHS was terminated early due to the emergence of an extreme 44% reduction in risk of a first heart attack among those assigned at random to aspirin. There have been four primary prevention trials published since then, three of which showed similar positive findings for aspirin.

"We found that the current totality of evidence strongly supports our initial findings from the Physicians’ Health Study that aspirin significantly reduces the risk of a first heart attack in apparently healthy individuals," added Dr. Hennekens. "These data, along with the findings that aspirin reduces the risk of death by 23% if given during a heart attack and by 15% in a wide range of people who have survived prior cardiovascular events, demonstrate that more widespread and appropriate use of aspirin in secondary and primary prevention would avoid many premature deaths and heart attacks."

Coronary heart disease is the single leading cause of death in the United States, accounting for more than 500,000 deaths annually. Approximately 80% of deaths from coronary heart disease in people under age 65 occur during the first heart attack.


###
Mount Sinai & Miami Heart’s Cardiovascular Center of Excellence is committed to being a leader in the prevention, diagnosis and treatment of heart disease. The medical center is the largest cardiac services provider in South Florida, conducting approximately 1,300 open heart procedures and approximately 7,400 diagnostic and therapeutic cardiac catheterizations annually. For a physician referral, please call (305) 674-2273.

Lauren Mazzella | EurekAlert!

More articles from Health and Medicine:

nachricht NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)

nachricht High speed video recording precisely measures blood cell velocity
15.11.2017 | ITMO University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

NASA detects solar flare pulses at Sun and Earth

17.11.2017 | Physics and Astronomy

NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures

17.11.2017 | Health and Medicine

The importance of biodiversity in forests could increase due to climate change

17.11.2017 | Studies and Analyses

VideoLinks
B2B-VideoLinks
More VideoLinks >>>