Scientists at UCLAs Jonsson Cancer Center have developed the worlds first animal model for mature human B-cell lymphomas, a discovery that may lead to the uncovering of the genetic mutations that cause these types of cancer. Mature B-cell type lymphomas account for about 85 percent of all lymphomas.
The basic science discovery is outlined in the Oct. 29 issue of the peer-reviewed journal Proceedings of the National Academy of Sciences.
"What we can do now is grow cell lines out of this model to determine which cancer-causing companion mutations arise," said Dr. Mike Teitell, a physician and researcher at UCLAs Jonsson Cancer Center and the lead author of the article, available online at www.pnas.org/. "This model appears to yield a large spectrum of mature B-cell lymphomas."
Kim Irwin | EurekAlert!
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