Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Excavated Jericho Bones May Help Israeli-Palestinian-German Team Combat Tuberculosis

14.07.2008
Six-thousand year old bones excavated in Jericho may help a joint Israeli-Palestinian-German research group combat tuberculosis.

According to Prof. Mark Spigelman of the Kuvin Center for the Study of Infectious and Tropical Diseases at the Hebrew University of Jerusalem, who is leading the Israeli team, the bones, which were all excavated by Dr. Kathleen Kenyon between fifty and seventy years ago, will be tested for tuberculosis, leprosy, leishmania and malaria. However, the primary focus will be tuberculosis.

Spigelman is known for his pioneering studies of ancient diseases (palaeoepidemiology) found on mummified bodies and human remains from Hungary and Korea to Sudan, in his quest to provide answers to the development of diseases affecting us today, such as tuberculosis, hepatitis and malaria.

'TB still the biggest killer'

Tuberculosis - or TB - is a deadly infectious bacterial disease that usually attacks the lungs. Acknowledged as a disease of crowds, it is transmitted from human to human living in close contact.

Dating back thousands of years, tuberculosis was well known in antiquity. However, according to Spigelman, it is still the biggest killer even today. One-third of the world's current population has been infected by tuberculosis, resulting, in recent years, in approximately three million deaths per year.

Why Jericho?

While the origins of tuberculosis and its evolution remain unclear, it is thought it came from the first villages and small towns in the Fertile Crescent region about 9-10,000 years ago. Jericho is one of the earliest towns on earth, dating back to 9,000 B.C., and so a lot of communicable - or town - diseases would have had a good start in this community.

By examining human and animal bones from this site, the researchers will be able to see how the first people living in a crowded situation developed the diseases of crowds and how this affected the disease through changes in DNA – of both the microbes and the people.

The most significant results of this research will come from a comparison between those data for humans and corresponding animal remains which may allow the identification of animal-human vectors and their interaction.

How can this research help us today?

Preliminary work suggests that there is sufficient DNA in the bone samples to make a contribution to our understanding of the origin and development of microbial disease which could provide crucial information in the evolution of tuberculosis.

Spigelman believes that knowing how a disease developed 6,000 years ago helps us understand what it will do as it continues to evolve, and will ultimately alter the practice of public health officials in combating it.

Where were the bones until now?

Spigelman came across the long-forgotten bones while examining mummies at Sydney University's Nicholson Museum.

“They told me they had lots of boxes of bones and didn’t know what they were because they’d been deposited there fifty years earlier by an anthropologist who’d worked with Dr. Kathleen Kenyon who’d been excavating at Jericho. When I examined them, I recognized that these were the bones from Jericho, and I told them not throw them out!”

Some of the bones, which were then brought to Israel by Spigelman while on a Sir Zelman Cowan Fund fellowship, will be studied along with other bones from Jericho that have been contributed by the Duckworth Collection at Cambridge University who have agreed to participate in the project.

Israeli-Palestinian-German cooperation

The research, which is being sponsored by a grant from the German Science Foundation, Deutsche Forschungsgemeinschaft (DFG), will be conducted by the Hebrew University, Al Quds University and the Ludwig-Maximilians University, Munich. In Israel, Ph.D. and master’s students from both Al-Quds and the Hebrew Universities will devote their time exclusively to this project.

According to Spigelman, the project will also help the Palestinians develop the technology and set up their own ancient DNA lab at Al Quds University.

This is one of eleven trilateral research projects at the Hebrew University involving Palestinian, Israeli and German cooperation.

For further information, contact:

Rebecca Zeffert, Dept. of Media Relations, the Hebrew University, tel: 02-588-1641, cell: 054-882-0661

or Orit Sulitzeanu, Hebrew University spokesperson, tel: 02-5882910, cell: 054-882-0016.

Internet site: http://media.huji.ac.il

Rebecca Zeffert | Hebrew University of Jerusalem
Further information:
http://www.huji.ac.il

More articles from Health and Medicine:

nachricht Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Microhotplates for a smart gas sensor

22.02.2017 | Power and Electrical Engineering

Scientists unlock ability to generate new sensory hair cells

22.02.2017 | Life Sciences

Prediction: More gas-giants will be found orbiting Sun-like stars

22.02.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>