Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sunburn alert: UVB does more damage to DNA than UVA

03.07.2008
New report in the FASEB Journal may lead to independence from skin cancer

As bombs burst in air this July 4, chances are that sunburn will be the red glare that most folks see – and feel. But unfortunately, even when there is no burn, the effects of the sun's ultraviolet (UV) rays can have deadly consequences.

Thanks to a new research study published in the July 2008 issue of The FASEB Journal, scientists now know why one type of UV light (UVB) is more likely to cause skin cancer than the other (UVA). This information should be useful to public health officials and government regulatory agencies in identifying specific criteria for exactly how effective consumer products, like sunscreen, are in preventing skin damage leading to skin cancer. It should also allow scientists to pursue new lines of research and treatment into repairing the damage caused by the sun's rays.

"Our study is novel in that it fills the gaps in knowledge of mechanisms involved in sunlight-associated skin cancers, which cover various aspects of DNA damage and repair and genetic alterations," said Ahmad Besaratinia, PhD, Assistant Research Scientist at City of Hope National Medical Center and first author on the report.

According to researchers from City of Hope National Medical Center in Duarte, California, UVB light is more harmful to our skin because our bodies are less able to repair the DNA damage it causes than the damage caused by UVA light. To reach their conclusions, scientists exposed three sets of cells to UVA light, UVB light and simulated sunlight. Then they compared these cells to an unexposed control group to analyze how well these cells were able to repair the damage. In addition, they analyzed published data on the genetics involved in human skin cancers. The researchers found that cells were more easily able to repair the damage caused by the UVA light, which explains why UVA light has been perceived as "safer" than UVB light. Despite this perception, scientists and public health experts caution that UVA light can and does cause serious damage that can and does lead to skin cancer.

"We know that sunlight causes skin cancer and that breakdown of the ozone layer exposes us to ever more ultraviolet radiation. This work tells us that both forms of UVA and UVB in sunlight cause damage to DNA. It forms a missing link in the chain of events from sun exposure to tumor formation," said Gerald Weissmann, MD, Editor-in-Chief of The FASEB Journal. "This research article gives us information that could lead to better sunscreens or effective 'after sun' products. It promises new ways to prevent - and perhaps to treat - the epidemic of skin cancer brought on by modern life."

Cody Mooneyhan | EurekAlert!
Further information:
http://www.fasebj.org

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

Im Focus: Using graphene to create quantum bits

In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.

In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...

Im Focus: Bacteria harness the lotus effect to protect themselves

Biofilms: Researchers find the causes of water-repelling properties

Dental plaque and the viscous brown slime in drainpipes are two familiar examples of bacterial biofilms. Removing such bacterial depositions from surfaces is...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

Innovation 4.0: Shaping a humane fourth industrial revolution

17.05.2017 | Event News

 
Latest News

Scientists propose synestia, a new type of planetary object

23.05.2017 | Physics and Astronomy

Zap! Graphene is bad news for bacteria

23.05.2017 | Life Sciences

Medical gamma-ray camera is now palm-sized

23.05.2017 | Medical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>