The scientists studied the brain activity of healthy subjects as they performed a task that was part of a training program and two untrained tasks. Their performance on the trained task and one of the untrained tasks improved. What these two tasks had in common was the activation of the striatum, a cluster of neuronal nuclei in midbrain.
The study involved a group of older (over 65 years) and younger (20-30 years old) subjects, who were asked to participate in a training program to update information in working memory. After five weeks, both groups showed clear improvement on the trained tasks. The transfer effect was limited, but in the younger group transfer was observed to another test involving memory updating.
To examine the neural systems involved, the scientists studied their subjects' brains using functional magnetic resonance imaging before and after training. During scanning, they performed a verbal updating task from the training program, a non-trained numerical task, which also required updating, and a non-trained task that did not require this skill. All tasks activated areas in the frontal cortex before training. In the younger group, the striatum was also activated during the updating tasks. After training, the striatum was activated during the trained task in both groups, and during the non-trained updating task in the younger group.
Altogether, the findings show that transfer is possible when both the trained and the non-trained tasks engage specific and overlapping brain systems, which is something to be borne in mind when developing and running training and rehabilitation programs. The striatum is a critical region in the updating of the working memory, and age-related changes here can inhibit the effects of both training and transfer.
The study was a joint project between scientists at Umeå University and Karolinska Institutet under a network (Nordic Centre of Excellence in Cognitive Control) financed by the Joint Committee for Nordic Research Councils for the Humanities and the Social Sciences (NOS-HS). The work is being done at the Umeå Centre for Functional Brain Imaging (UFBI) and the authors of the paper are Erika Dahlin (Department of Integrative Medical Biology, Umeå University), Anna Stigsdotter Neely (Department of Psychology, Umeå University), Anne Larsson (Radiophysical Unit, Umeå University), Lars Bäckman (Department of Neurobiology, Care Sciences and Society, KI) and Lars Nyberg (Department of Integrative Medical Biology and Department of Radiation Sciences, Umeå University).For further information, contact either Professor Lars Nyberg at +46 (0)90-785 33 64 or +46 (0)90-786 64 29, or via firstname.lastname@example.org;
or Professor Lars Bäckman at +46 (0)8-690 58 26 or +46 (0)70-5934513 or via email@example.com
Hans Fällman | idw
Speed data for the brain’s navigation system
06.12.2016 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)
Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
07.12.2016 | Earth Sciences
07.12.2016 | Earth Sciences
07.12.2016 | Materials Sciences