“Animal tests have shown acrylamide to be a carcinogen, but until recently no studies have demonstrated a link between acrylamide in foods and cancer in humans. Ours is the first epidemiological study using biological markers for measuring acrylamide exposure, and the first to report a positive association between acrylamide and breast cancer,” says Henrik Frandsen, senior scientist at the National Food Institute, Technical University of Denmark.
All previous epidemiological studies have been based on food frequency questionnaires. The scientists behind this study have instead used biological markers to be able to more accurately determine the acrylamide levels ingested by the women participating in the study. The women’s blood has been tested for the level of acrylamide bound to haemoglobin in red blood cells.
The findings show a positive association between an increased acrylamide-haemoglobin level and the development of breast cancer after adjustment for smoking behaviour. The risk of breast cancer doubles with a tenfold increase in the acrylamide-haemoglobin level. A tenfold increase in the acrylamide-haemoglobin level corresponds more or less to the difference measured between the women with the lowest and highest exposure. The study also shows a stronger association for estrogen receptor positive breast cancer.Further research required
“It is, however, important to stress that neither study indicates an unambiguous association between acrylamide in foods and cancer. It is, for example, uncertain whether the observed effect on breast cancer is instead related to other chemical compounds formed along with acrylamide during the heating of foods. Another uncertainty is whether some of the acrylamide originates from sources other than foods,” says Pelle Thonning Olesen, scientist at the National Food Institute, Technical University of Denmark.
“Further research into the potential adverse effects of acrylamide is imperative before any definite conclusions can be drawn on the significance of the substance for cancer in general. At the same time, it emphasises the importance of continuing the research and initiatives aimed to reduce acrylamide levels in the human diet,” adds Anne Tjønneland, chief physician at the Danish Cancer Society.Read more
The research project was conducted by scientists from the National Food Institute, Technical University of Denmark in collaboration with the Institute of Cancer Epidemiology, the Danish Cancer Society as part of the HEATOX EU project. See www.heatox.org for information about how to manage the acrylamide risk.
The project was funded by the EU’s Sixth Framework Programme and by a grant from the Nordic Council of Ministers and was completed with support from the National Food Institute, Technical University of Denmark and the Danish Cancer Society.Contact
Peter Hoffmann | alfa
Light beam replaces blood test during heart surgery
28.02.2017 | University of Central Florida
Cells adapt ultra-rapidly to zero gravity
28.02.2017 | Universität Zürich
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
28.02.2017 | Life Sciences
28.02.2017 | Power and Electrical Engineering
28.02.2017 | Information Technology