Over 30 000 Swedish men and women may have raised levels of prolactin. Women who are pregnant or breast feeding have naturally raised levels of prolactin, but stress, some medicines and benign brain tumours can also lead to raised levels of the hormone.
"In recent years scientists have also recognised the role of prolactin in the development of obesity, but little research has been done into the precise mechanism by which prolactin regulates metabolism," says Louise Nilsson.
In her thesis Louise Nilsson shows that there are receptors for the breast feeding hormone in human fatty tissue.
"We have demonstrated that prolactin reduces the ability of fatty tissue to store sugar and fat, which then could accumulate in the blood and certain tissues instead. This in turn increases the risk of cardiovascular disease."
Prolactin also affects the body's ability to metabolise fat. An ongoing study suggests that the hormone impairs the body's ability to maintain a balanced metabolism.
"When fatty tissue receives signals from prolactin, it reacts by reducing the production of another hormone called adiponectin, which is important for the metabolism of a variety of nutrients," explains Louise Nilsson.FACTS ABOUT PROLACTIN
The Sahlgrenska Academy is the faculty of health sciences at the University of Gothenburg, Sweden. Education and research are conducted within the fields of pharmacy, medicine, odontology and health care sciences.
About 4000 undergraduate students and 1000 postgraduate students are enrolled at Sahlgrenska Academy. The staff is about 1500 persons. 850 of them are researchers and/or teachers.For further information please contact:
Doctoral thesis from the Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg, Sweden.
Title of thesis: Effects of prolactin on metabolism - changes induced by hyperprolactinemiaThe thesis has been defended.
Finnish research group discovers a new immune system regulator
23.02.2018 | University of Turku
Minimising risks of transplants
22.02.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
23.02.2018 | Physics and Astronomy
23.02.2018 | Health and Medicine
23.02.2018 | Physics and Astronomy