Childhood allergies have increased significantly in industrialized countries during the past few decades. Researchers theorize that this rising incidence is the result of a lowered exposure to bacteria in early childhood.
This exposure to microbes appears to be essential in jump-starting the immune system to develop healthy pathways that do not result in allergic conditions.
Additionally, it’s been observed that infants who develop allergies have intestinal bacteria that are distinctly different from those of non-allergic infants, suggesting that the type of intestinal microflora is an important factor in forming allergic conditions.
In a study published in the Journal of Allergy and Clinical Immunology (online January 2009) researchers from the University and University Central Hospital of Helsinki conducted a clinical trial of more than 1200 mothers whose infants would be at high risk to develop allergies. During the last month of their pregnancies, the mothers took daily doses of a probiotic mixture or a placebo, and their infants were given the same probiotic mixture plus a prebiotic or a placebo for the first 6 months of their lives. The children were followed for 5 years and evaluated for incidence of allergic diseases.
The authors found that the frequencies of allergic and IgE-associated allergic disease and sensitization were similar in the children who had received probiotic and those who’d gotten placebo. Although there appeared to be a preventive effect at age 2, there was none noted at age 5. Interestingly, in babies born by cesarean section, the researchers found less IgE-associated allergic disease in those who had received the probiotic.
“No allergy-preventive effect is extended to age 5 years by perinatal supplementation with probiotics in babies at risk for developing allergies; protection is conferred only to C-section babies”, says Dr. Mikael Kuitunen from the University Central Hospital of Helsinki. “However, it is possible that stronger and longer stimulation of the infant immune system possibly by varying the strains of bacteria, may result in better allergy-preventive effects.”
Paivi Lehtinen | alfa
PET imaging tracks Zika virus infection, disease progression in mouse model
20.09.2017 | US Army Medical Research Institute of Infectious Diseases
'Exciting' discovery on path to develop new type of vaccine to treat global viruses
18.09.2017 | University of Southampton
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
20.09.2017 | Life Sciences
20.09.2017 | Power and Electrical Engineering
20.09.2017 | Physics and Astronomy