Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Ordinary chickens may be extraordinary in fighting cancer, says Texas A&M researcher

11.07.2012
The common barnyard chicken could provide some very un-common clues for fighting off diseases and might even offer new ways to attack cancer, according to a team of international researchers that includes a Texas A&M University professor.

James Womack, Distinguished Professor of Veterinary Pathobiology in the College of Veterinary Medicine & Biomedical Sciences, is co-author of a paper detailing the team's work that appears in the current issue of PNAS (Proceedings of the National Academy of Sciences). Womack was a leader in the international effort to sequence the cattle genome in 2004.

Womack and the team, comprised mostly of scientists from the Seoul National University in Korea, examined 62 White Leghorn and 53 Cornish chickens for diversity in NK-lysin, an antibacterial substance that occurs naturally in animals and is used as a method of fighting off diseases.

They were able to obtain two genetic variations of NK-lysin and the results offered two unexpected shockers: both showed abilities to fight off bacterial infections and other diseases, while one showed it could successfully fight cancer cells as well.

"It took all of us by surprise," Womack says of the findings.

"One of the genetic variations shows it has the ability to fight against cancer cells much more aggressively than the other variation. We certainly were not looking at the cancer side of this, but there it was."

Womack says the team selected the two breeds because Cornish and White Leghorn chickens, found throughout most of the world, have relatively diverse genetic origins.

After conducting a DNA sequence of the chickens, the team found two variations of the genes that offered clues as to their protective ability to ward off infections.

"One form appears to be more potent in killing off cancer cells than the other, and that's the one that naturally caught our eye," Womack adds.

"This could lead to other steps to fight cancer or in developing ways to prevent certain infections or even diseases. It's another door that has been opened up. We are looking at similar studies right now to see if this is possible with cattle.

"The next step is to work with other animals and see if similar variants exist. We need to look for any genetic similarities to the chicken variants and then determine if these variants affect the health of the animal, but this is an exciting first step in this direction."

Media contact: Keith Randall, News & Information Services, at (979) 845-4644 or keith-randall@tamu.edu; or James Womack at (979) 845-9810 or jwomack@cvm.tamu.edu

More news about Texas A&M University, go to http://tamutimes.tamu.edu/

Follow us on Twitter at http://twitter.com/tamu/

Keith Randall | EurekAlert!
Further information:
http://www.tamu.edu

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>