Published in the journal Science and Technology of Advanced Materials, the paper summarizes the current state of knowledge on nanotechnology with application to stem cell biology. (The term “nanotechnology” refers to the design, construction, generation and use of nanoscale (1-100 nm) structures or materials.)
Stem cells are considered an important potential source for repairing damaged human tissues. Researchers have found that the adhesion, growth, and differentiation of stem cells are likely controlled by their surrounding microenvironment, which contains both chemical and physical cues. These cues include the “nanotopography” of the complex extracellular matrix or architecture that forms a network for human tissues.
In their review paper, Yang-Kao Wang and colleagues describe studies showing how this nanotopography (which includes nanosized pores, grooves, ridges, etc.) plays important roles in the behaviour and fate of stem cells. The authors also discuss the application of nanoparticles to stem cell isolation, tracking and imaging; how to translate nanotechnology from two to three dimensions; and the potential limitations of using nanomaterials in stem cell biology.
The paper concludes that “understanding [the] interactions of nanomaterials with stem cells may provide knowledge applicable to [the development of improved] cell-scaffold combinations in tissue engineering and regenerative medicine.”
For more information about this paper, please contact:Yang-Kao Wang
Mikiko Tanifuji | EurekAlert!
A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital
Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
24.04.2017 | Physics and Astronomy
24.04.2017 | Materials Sciences
24.04.2017 | Life Sciences