Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Mountaineers measure lowest human blood oxygen levels on record

08.01.2009
The lowest ever levels of oxygen in humans have been reported in climbers on an expedition led by UCL (University College London) doctors.

The world-first measurements of blood oxygen levels in climbers near the top of Mount Everest, published in this week’s New England Journal of Medicine (NEJM), could eventually help critical care doctors to re-evaluate treatment strategies in some long-term patients with similarly low levels of blood oxygen.

The Caudwell Xtreme Everest team of climbing doctors made the measurements by taking blood from leg arteries close to the summit of Mount Everest at 8,400 metres above sea-level. The team climbed with oxygen tanks, then removed their masks 20 minutes prior to testing to equilibrate their lungs with the low-oxygen atmosphere. The team were unable to make the measurement on the summit of Everest as conditions were too severe, with temperatures at minus 25 degrees centrigrade and winds above 20 knots.

Having descended a short distance from the summit, the doctors removed their gloves, unzipped their down suits and drew blood from the femoral artery in the groin. Blood collected from four team members was then carried back down the mountain to be analysed within two hours at a science laboratory set up at the team’s camp at 6,400 metres on Everest.

The purpose of the study was to establish what has long been suspected – that high-altitude climbers have incredibly low levels of oxygen in their blood, which at sea-level would only be seen in patients close to death. The expedition found the average arterial oxygen level to be 3.28 kilopascals or kPa (with the lowest value being 2.55 kPa); the normal value in humans is 12-14 kPa and patients with a level below 8 kPa are considered critically ill. Based on calculations of the expected level of oxygen in the blood, the authors also speculate that accumulation of fluid in the lungs as a result of the high altitude might have contributed to the low oxygen levels.

Caudwell Xtreme Everest expedition leader Dr Mike Grocott, a UCL Senior Lecturer in Critical Care Medicine, said: “By observing healthy individuals at high altitude where oxygen is scarce, we can learn about physiological changes that can improve critical care at the hospital bedside, because low oxygen levels are an almost universal problem in critical care. These extraordinary low levels of oxygen found in high-altitude climbers may cause doctors looking after critically ill patients to revaluate treatment goals in some patients who have been ill for some time and might have adapted to low levels of oxygen in the blood. However, our findings will need further careful evaluation before they can be translated into clinical practice. We hope that ongoing research will eventually lead to better treatments for patients with acute respiratory distress syndrome (ARDS), cystic fibrosis, emphysema, septic shock, ‘blue baby’ syndrome and other critical illnesses.”

Jenny Gimpel | alfa
Further information:
http://www.ucl.ac.uk

More articles from Health and Medicine:

nachricht Cystic fibrosis alters the structure of mucus in airways
28.06.2017 | University of Iowa Health Care

nachricht Mice provide insight into genetics of autism spectrum disorders
28.06.2017 | University of California - Davis

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Supersensitive through quantum entanglement

28.06.2017 | Physics and Astronomy

X-ray photoelectron spectroscopy under real ambient pressure conditions

28.06.2017 | Physics and Astronomy

Mice provide insight into genetics of autism spectrum disorders

28.06.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>