In an animal model of PTSD, high doses of a cortisol-related substance, corticosterone, prevented negative consequences of stress exposure, including increased startle response and behavioral freezing when exposed to reminders of the stress.
Cortisol is secreted into the blood stream through the adrenal glands, which are active when the body responds to stress. It is known as "the stress hormone" because it is also secreted in higher levels during the body's "fight or flight" response to stress, and is responsible for several stress-related changes in the body.
According to Dr. Hagit Cohen of the Anxiety and Stress Research Unit at the Faculty of Health Sciences, Ben-Gurion University of the Negev, "A single intervention with high-dose corticosterone immediately after exposure to a psychogenic stressor was highly effective in reducing the incidence of PTSD-like behaviors and improved the resilience to subsequent trauma-cue exposure in an innovative controlled prospective animal study."
"Single high-dose corticosteroid treatment may thus be worthy of clinical investigation as a possible avenue for early pharmaco-therapeutic intervention in the acute phase, aimed at prevention of chronic stress-related disorders, such as PTSD," Cohen explains. "In this sense, it brings treatment of PTSD to a new era – an era of secondary prevention, an era of the golden hours."
How prenatal maternal infections may affect genetic factors in Autism spectrum disorder
22.03.2017 | University of California - San Diego
22.03.2017 | Empa - Eidgenössische Materialprüfungs- und Forschungsanstalt
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
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22.03.2017 | Physics and Astronomy
22.03.2017 | Materials Sciences