In an animal model of PTSD, high doses of a cortisol-related substance, corticosterone, prevented negative consequences of stress exposure, including increased startle response and behavioral freezing when exposed to reminders of the stress.
Cortisol is secreted into the blood stream through the adrenal glands, which are active when the body responds to stress. It is known as "the stress hormone" because it is also secreted in higher levels during the body's "fight or flight" response to stress, and is responsible for several stress-related changes in the body.
According to Dr. Hagit Cohen of the Anxiety and Stress Research Unit at the Faculty of Health Sciences, Ben-Gurion University of the Negev, "A single intervention with high-dose corticosterone immediately after exposure to a psychogenic stressor was highly effective in reducing the incidence of PTSD-like behaviors and improved the resilience to subsequent trauma-cue exposure in an innovative controlled prospective animal study."
"Single high-dose corticosteroid treatment may thus be worthy of clinical investigation as a possible avenue for early pharmaco-therapeutic intervention in the acute phase, aimed at prevention of chronic stress-related disorders, such as PTSD," Cohen explains. "In this sense, it brings treatment of PTSD to a new era – an era of secondary prevention, an era of the golden hours."
A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital
Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...
Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.
A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
21.04.2017 | Physics and Astronomy
21.04.2017 | Health and Medicine
21.04.2017 | Physics and Astronomy