These words are from the cancer physician Olof Ståhl, who has studied this issue in his coming dissertation from Lund University in Sweden.
It is known that undergoing radiation treatment and chemotherapy can affect male fertility. For this reason, attempts are always made nowadays to preserve and freeze sperm before cancer treatment starts. Just how fertility is affected then depends on the type of cancer and the type of treatment. The result can be anything from unaffected sperm production to complete loss of sperm production, with a middle group where production is impacted in a way that leaves fewer sperms with impaired mobility.
The question of possible connections between cancer and the risk of deformities in future children has been less thoroughly addressed. Can cancer have affected the sperms even though sperm production as such is entirely normal? And in cases requiring in vitro fertilization, IVF, is there a risk of using sperms that need help carrying out fertilization but also are bearing damaged genes? These issues have never been studied before.
Olof Ståhl and his associates have now addressed the questions in a register study of 1.8 million children in Denmark and Sweden, born between 1994 and 2005. All children with deformities (chromosome disturbances, cleft palate, heart malformations, etc.) were pulled from the register and compared with data about possible cancers in their fathers and whether they were fertilized normally or via IVF. The study shows that there is a slightly elevated risk for deformity both among children born to former cancer patients and among children conceived via test-tube fertilization. The latter risk is already known, and it is regarded to be not so much due to IVF methods as to the fact that sperms that require IVF are of poorer quality. The risk elevation is small, however: from 3.2 percent - the 'natural' risk of deformity in children - to 3.7 percent and 3.8 percent respectively.
"This is such a tiny difference that it is virtually negligible. We also found that the combination of father-with-previous-cancer and IVF did not entail any further increase in risk. This is a great relief for former cancer patients who might be worried about the health of their future children," claims Olof Ståhl.
The study is so new that it has not yet been published. The three other studies included in the dissertation were published in the journals Cancer, Human Reproduction, and International Journal of Andrology.
Olof Ståhl, who will publicly defend his dissertation on December 12, can be reached at cell phone: +46 (0)706-696960 or phone: +46 (0)46/177702; e-mail email@example.com.
Pressofficer Ingela Björck, firstname.lastname@example.org; +46-46 222 7646
Ingela Bjöck | idw
Inflammation Triggers Unsustainable Immune Response to Chronic Viral Infection
24.10.2016 | Universität Basel
Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg
Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
25.10.2016 | Earth Sciences
25.10.2016 | Power and Electrical Engineering
25.10.2016 | Process Engineering