Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Good news for young male cancer patients

12.12.2008
"Young men undergoing treatment for cancer often want to know how the disease and its treatment affect their chances of fathering healthy children. Our large-scale study shows that there is a slightly higher risk of deformities, but the actual risk of having a child with deformities is nevertheless extremely low. I think this is good news!"

These words are from the cancer physician Olof Ståhl, who has studied this issue in his coming dissertation from Lund University in Sweden.

It is known that undergoing radiation treatment and chemotherapy can affect male fertility. For this reason, attempts are always made nowadays to preserve and freeze sperm before cancer treatment starts. Just how fertility is affected then depends on the type of cancer and the type of treatment. The result can be anything from unaffected sperm production to complete loss of sperm production, with a middle group where production is impacted in a way that leaves fewer sperms with impaired mobility.

The question of possible connections between cancer and the risk of deformities in future children has been less thoroughly addressed. Can cancer have affected the sperms even though sperm production as such is entirely normal? And in cases requiring in vitro fertilization, IVF, is there a risk of using sperms that need help carrying out fertilization but also are bearing damaged genes? These issues have never been studied before.

Olof Ståhl and his associates have now addressed the questions in a register study of 1.8 million children in Denmark and Sweden, born between 1994 and 2005. All children with deformities (chromosome disturbances, cleft palate, heart malformations, etc.) were pulled from the register and compared with data about possible cancers in their fathers and whether they were fertilized normally or via IVF. The study shows that there is a slightly elevated risk for deformity both among children born to former cancer patients and among children conceived via test-tube fertilization. The latter risk is already known, and it is regarded to be not so much due to IVF methods as to the fact that sperms that require IVF are of poorer quality. The risk elevation is small, however: from 3.2 percent - the 'natural' risk of deformity in children - to 3.7 percent and 3.8 percent respectively.

"This is such a tiny difference that it is virtually negligible. We also found that the combination of father-with-previous-cancer and IVF did not entail any further increase in risk. This is a great relief for former cancer patients who might be worried about the health of their future children," claims Olof Ståhl.

The study is so new that it has not yet been published. The three other studies included in the dissertation were published in the journals Cancer, Human Reproduction, and International Journal of Andrology.

Olof Ståhl, who will publicly defend his dissertation on December 12, can be reached at cell phone: +46 (0)706-696960 or phone: +46 (0)46/177702; e-mail olof.stahl@med.lu.se.

Pressofficer Ingela Björck, ingela.bjorck@info.lu.se; +46-46 222 7646

Ingela Bjöck | idw
Further information:
http://www.lu.se/o.o.i.s?id=12588&postid=1268572

Further reports about: Cancer treatment IVF cancer patients healthy children sperm production

More articles from Health and Medicine:

nachricht NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)

nachricht High speed video recording precisely measures blood cell velocity
15.11.2017 | ITMO University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

NASA detects solar flare pulses at Sun and Earth

17.11.2017 | Physics and Astronomy

NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures

17.11.2017 | Health and Medicine

The importance of biodiversity in forests could increase due to climate change

17.11.2017 | Studies and Analyses

VideoLinks
B2B-VideoLinks
More VideoLinks >>>