These words are from the cancer physician Olof Ståhl, who has studied this issue in his coming dissertation from Lund University in Sweden.
It is known that undergoing radiation treatment and chemotherapy can affect male fertility. For this reason, attempts are always made nowadays to preserve and freeze sperm before cancer treatment starts. Just how fertility is affected then depends on the type of cancer and the type of treatment. The result can be anything from unaffected sperm production to complete loss of sperm production, with a middle group where production is impacted in a way that leaves fewer sperms with impaired mobility.
The question of possible connections between cancer and the risk of deformities in future children has been less thoroughly addressed. Can cancer have affected the sperms even though sperm production as such is entirely normal? And in cases requiring in vitro fertilization, IVF, is there a risk of using sperms that need help carrying out fertilization but also are bearing damaged genes? These issues have never been studied before.
Olof Ståhl and his associates have now addressed the questions in a register study of 1.8 million children in Denmark and Sweden, born between 1994 and 2005. All children with deformities (chromosome disturbances, cleft palate, heart malformations, etc.) were pulled from the register and compared with data about possible cancers in their fathers and whether they were fertilized normally or via IVF. The study shows that there is a slightly elevated risk for deformity both among children born to former cancer patients and among children conceived via test-tube fertilization. The latter risk is already known, and it is regarded to be not so much due to IVF methods as to the fact that sperms that require IVF are of poorer quality. The risk elevation is small, however: from 3.2 percent - the 'natural' risk of deformity in children - to 3.7 percent and 3.8 percent respectively.
"This is such a tiny difference that it is virtually negligible. We also found that the combination of father-with-previous-cancer and IVF did not entail any further increase in risk. This is a great relief for former cancer patients who might be worried about the health of their future children," claims Olof Ståhl.
The study is so new that it has not yet been published. The three other studies included in the dissertation were published in the journals Cancer, Human Reproduction, and International Journal of Andrology.
Olof Ståhl, who will publicly defend his dissertation on December 12, can be reached at cell phone: +46 (0)706-696960 or phone: +46 (0)46/177702; e-mail email@example.com.
Pressofficer Ingela Björck, firstname.lastname@example.org; +46-46 222 7646
Ingela Bjöck | idw
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences