To determine average glucose levels in the blood over a two to three month period, doctors measure glycosylated hemoglobin (the oxygen-carrying protein in the blood that is bound to the sugar glucose). In general, higher levels have been associated with increased risk of heart disease, said Dr. David Aguilar, assistant professor of medicine – cardiology at BCM (http://www.bcm.edu/news/broadcastcenter/expert.cfm?expertid=150).
"Most doctors try to keep glucose levels of those with diabetes as low as they can to lower the risk of complications such as eye problems, kidney disease or the development of heart disease," said Aguilar, senior author of the study. "However, we found that in diabetic patients with heart failure, glucose levels slightly higher than what are normally recommended had the lowest risk of death."
Researchers at BCM and the Michael E. DeBakey Veterans Affairs Medical Center (http://www.houston.va.gov/) in Houston identified 5,815 veterans with heart failure and diabetes who were receiving treatment at VA medical centers across the nation. They followed the patients for two years, dividing them into five categories based on their glycosylated hemoglobin levels.
Most medical professionals recommend levels at 7 and below as the target for optimal health for diabetic patients. However, the results of the study of diabetic patients with heart failure showed that those with levels 7.1 to 7.8 had the lowest rate of death. Those patients at both ends of the spectrum had the higher death risks.
"This doesn't mean that diabetic patients with heart failure should change their target goal for glucose levels," Aguilar said. "The results could simply be telling us that the glycosylated hemoglobin levels are a marker for other risks that are contributing to increased risk of death, but not necessarily the cause of the problem."
Aguilar said the correlation needs to be further investigated to confirm the findings and see what other factors could be contributing to the mortality rate.
The research is supported by a V.A. Health Services Research and Development Service grants and a National Institutes of Health Mentored Career Development Award.
Other researchers who took part in this study include, Drs. Biykem Bozkurt, Kumudha Ramasubbu and Anita Deswal, all from the Winters Center for Heart Failure Research and Section of Cardiology, and the Department of Medicine at BCM. Deswal is also at the Houston Center for Quality of Care and Utilization Studies at the Michael E. DeBakey V. A. Medical Center in Houston.
Graciela Gutierrez | EurekAlert!
NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)
High speed video recording precisely measures blood cell velocity
15.11.2017 | ITMO University
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...
Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
20.11.2017 | Earth Sciences
20.11.2017 | Earth Sciences
20.11.2017 | Life Sciences