About 35 per cent of all diabetes patients suffer from gastroparesis, which is a medical condition where the stomach is partly paralysed. As a result of the paralysis, food remains in the stomach for a longer time than normal.
Researchers at the Sahlgrenska Academy, University of Gothenburg, have now shown that dietary modifications can reduce the patients’ symptoms.
In the study, which involved 56 diabetes patients with gastroparesis, the subjects who were put on a small particle diet (smaller than 2 mm in diameter) experienced significantly less severe gastrointestinal symptoms than those who ate a conventional diabetes diet, which tends to focus on large particle foods.
Small particle foods can be defined as food items that fall apart like a boiled potato when mashed with a fork. Examples include boiled, baked and mashed potatoes, fish gratin, meat loaf and thin soups.
Patients who were put on this type of diet for at least 20 weeks experienced considerably fewer gastrointestinal symptoms such as vomiting, nausea, regurgitation, inability to finish a meal, bloating and lack of appetite.
‘Eating and the resulting symptoms can be very anxiety producing for gastroparesis patients. The subjects who were put on a small-particle diet experienced reduced anxiety levels,’ says Eva Olausson, who is presenting the study as part of her doctoral thesis at the Sahlgrenska Academy.
The study shows that particle size is directly correlated with the process of gastric emptying: the patients who were put on the small particle diet showed the same rates of gastric emptying as the healthy control group.
They also displayed more normal blood sugar responses than those found for large particle meals.
‘A small particle diet probably leads to fewer hypoglycemic events, and the events that do occur become easier to manage. This is of tremendous value to the patients,’ says Olausson.
Olausson’s thesis also shows that a large particle meal can be used to identify patients with gastroparesis, allowing for faster initiation of treatment.
The scientists have also developed a new method to diagnose gastroparesis, where patients swallow special markers that can be easily followed through the gastrointestinal system by fluoroscopy.
‘These two methods are easily accessible and could help reduce the number of unknown gastroparesis cases, which in turn could help reduce the costs to both patients and society in the form of medical treatments and sick-listings,’ says Olausson.
The thesis titled Diagnosis & Dietary Intervention in Patients with Diabetic Gastroparesis was publicly defended on 20 September.Contact:
Supervisor: Prof. Magnus Simrén, Sahlgrenska Academy, University of Gothenburg; email@example.comWeitere Informationen:
Torsten Arpi | idw
Penn vet research identifies new target for taming Ebola
12.01.2017 | University of Pennsylvania
The strange double life of Dab2
10.01.2017 | University of Miami Miller School of Medicine
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration
"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...
Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.
Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
16.01.2017 | Power and Electrical Engineering
16.01.2017 | Information Technology
16.01.2017 | Power and Electrical Engineering