Every tenth woman is afflicted with breast cancer during her lifetime.The diagnosis and treatment of a patient involves the collaboration of a wide range of specialists.
To improve this situation, VPH-PRISM partners are developing software for X-ray, MRI images, ultrasound, and histology from biopsies, to provide a unified display to spatially superimpose, measure, and manipulate these images. Especially helpful would be the ability to characterize the area surrounding a tumor more accurately. The project will aim to answer the questions: has this tissue changed to such a degree that it must be removed with the tumor during the operation, or can a more local excision, exposing the patient to a less invasive operation, be performed without the risk of recurrence?
To accomplish this, tissue sample pathology slides must be digitized. However, digitization generates large amounts of data, which pathologists can only partially inspect. To solve this, VPH-PRISM experts are also developing software that automatically preselects and preprocesses the data, thereby facilitating the work of the pathologist. If the venture is successful, experts estimate that digital pathology will promote a breakthrough in breast cancer care similar to the effect that the widespread introduction of mammography had on early detection that has occurred over the last 15 years.
The project will explore how a deep understanding of tissue microstructure, gleaned from histology, can aid interpretation of X-ray, MRI, and ultrasound images. Additionally challenging is the presentation of tissue sample images alongside MRI and X-ray images. Experts using computationally intensive algorithms must guarantee that multiple data sets fit perfectly together. Only in this manner can tissue parameters gathered using different scalings be spatially correlated and hence superimposed.The goal is a software tool that supports clinicians when choosing therapy. Patient data should be grouped automatically according to shared criteria. This allows the software to provide clues for optimal chemotherapy, for instance, if a patient with particular tissue characteristics has been assigned to a particular group. This could prove useful for monitoring the progress of therapy more accurately: Is the tumor degenerating as quickly as expected when a patient undergoes a certain type of chemotherapy? If not, then the doctor could cease ineffective therapy in a timely fashion and provide the patient with alternative drugs.
Penn study identifies new malaria parasites in wild bonobos
21.11.2017 | University of Pennsylvania School of Medicine
NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
21.11.2017 | Physics and Astronomy
21.11.2017 | Physics and Astronomy
21.11.2017 | Life Sciences