Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Breath or Urine Analysis May Detect Cancer, Diabetes

12.03.2009
MU researcher is developing a sensor that identifies volatile markers that indicate disease
A future sensor may take away a patient's breath while simultaneously determining whether the patient has breast cancer, lung cancer, diabetes or asthma. A University of Missouri researcher is developing a device that will analyze breath or urine samples for volatile markers inside the body that indicate disease. These volatile markers, such as alkanes, acetones or nitric oxide, give doctors clues about what is happening inside the body and can be used as a diagnostic tool.

"Little traces of certain gas molecules in the breath or urine tell us if anything unusual is going on in the body," said Xudong "Sherman" Fan, investigator in the Christopher S. Bond Life Sciences Center. "Measuring these volatile markers would be a non-invasive way to determine if a disease is present without having to draw blood or complete a biopsy. In addition to the biomarkers already discovered, many more potential volatile markers are still under investigation."
The sensor device known as the opto-fluidic ring resonator (OFRR) is an optical gas sensor that consists of a polymer-lined glass tube that guides the flow of a gas vapor and a ring resonator that detects the molecules that pass through the glass tube. As the gas vapor enters the device, molecules in the vapor separate and react to the polymer lining. Light makes thousands of loops around the gas or liquid sample. The more the light loops around the sample, the more the light energy interacts with the gas vapor. These repetitive interactions enable the detection of vapor molecules down to a very small quantity.

Optical gas sensors have broad applications in the fields of industry, military, environment, medical care and homeland security. In addition to OFRR's application in the medical industry, the device also can improve the detection of explosives on the battlefield. Currently, the existing gas vapor sensor technology is very bulky with equipment weighing more than 100 pounds and is difficult to use in the field.
"We hope to design a vapor sensor that has ultra-high sensitivity, specific and rapid response to a certain molecule, as well as the ability of on-the-spot chemical analyses, which usually requires the sensor to be small, portable, reusable and have less power consumption," said Fan, who also is assistant professor of biological engineering in the MU College of Engineering and the MU College of Agriculture, Food and Natural Resources. "If the gas sensor is portable, military personnel can determine more quickly whether an area is dangerous."

Fan's research is funded by the National Science Foundation and has been published in peer-reviewed journals such as Optics Letters, Optics Express and Analytical Chemistry.

Kelsey Jackson | EurekAlert!
Further information:
http://www.missouri.edu

More articles from Health and Medicine:

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

nachricht What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>