Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Air pollution damages more than lungs: Heart and blood vessels suffer too

14.08.2008
As athletes from around the world compete in the Beijing Olympics, many are on alert for respiratory problems caused by air pollution. They should also be concerned about its toxic effects on the heart and cardiovascular system, mounting research shows.

According to an article published in the August 26, 2008, issue of the Journal of the American College of Cardiology (JACC), air pollution has both short- and long-term toxic effects that injure the heart and blood vessels, increase rates of hospitalization for cardiac illness, and can even cause death.

"We used to think air pollution was a problem that primarily affects the lungs. We now know it is also bad for the heart," said Robert A. Kloner, M.D., Ph.D., director of research at the Heart Institute of the Good Samaritan Hospital, and a professor of medicine at the Keck School of Medicine, University of Southern California, both in Los Angeles.

When pollutants are inhaled, they trigger an increase in "reactive oxygen species"—superoxiding molecules that damage cells, cause inflammation in the lungs, and spark the cascade of harmful effects in the heart and cardiovascular system. Recent research suggests that ultrafine air pollutants, such as those coming from car exhaust, may pass into the blood stream and damage the heart and blood vessels directly. Hearts directly exposed to ultrafine air pollutants show an immediate decrease in both coronary blood flow and the heart's pumping function, as well as a tendency to develop arrhythmias, according to studies conducted at the Heart Institute.

"There doesn't have to be an environmental catastrophe for air pollution to cause injury," said Boris Z. Simkhovich, M.D., Ph.D, a senior research associate at the Heart Institute of the Good Samaritan Hospital, and an assistant professor of research medicine at the Keck School of Medicine, University of Southern California. "We're talking about very modest increases. Air pollution can be dangerous at levels that are within the accepted air quality standards."

Studies in both humans and animals have shown that exposure to air pollution can affect heart rate, blood pressure, blood vessel function, blood clotting, and heart rate variability (a factor in developing heart rhythm disturbances), and speed the progression of atherosclerosis.

Researchers who study large populations of people over time have found that increased levels of air pollution are linked to emergency hospital admissions for heart attack, chest pain, and congestive heart failure and even to death from heart disease, arrhythmias, heart failure and cardiac arrest.

The elderly and patients who have already been diagnosed with heart disease or diabetes (which damages the blood vessels) are particularly vulnerable to the cardiovascular effects of air pollution.

"Patients with cardiovascular disease shouldn't exercise outside on days with increased air pollution levels. On very polluted days, they should consider staying inside, and during the winter, they should limit exposure to fireplace smoke," Dr. Kloner said. "Of course, the real solution is to reduce air pollution."

Alfred Bove, M.D., Ph.D., agreed. "The review by Dr. Simkhovich and his fellow authors make it quite clear that air pollution is linked to cardiovascular disease," said Dr. Bove, ACC's president-elect and cardiology section chief at Temple University School of Medicine in Philadelphia. "They suggest that this is another compelling reason to campaign for improved air quality, while at the same time studying therapies to minimize the risk of exposures."

Amanda Jekowsky | EurekAlert!
Further information:
http://www.acc.org

Further reports about: Air Pollution Heart blood vessel heart failure superoxiding molecules

More articles from Health and Medicine:

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

nachricht What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>