Replacing both knees in one surgery, or simultaneous total knee replacement (TKR) was associated with significantly fewer prosthetic joint infections as well as other revision knee operations within one year after surgery, compared with total knee replacements performed in two separate procedures.
However, simultaneous replacement was associated with a moderately higher risk of adverse cardiovascular outcomes within 30 days, according to a study presented today at the 2011 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).
This study included 11,445 patients who underwent simultaneous bilateral knee replacement and 23,715 patients who had both knees replaced in two stages several months apart. Patients' mean ages were 67.2 years in the group who underwent simultaneous surgery and 67.7 years in the group who underwent two surgeries. The majority of patients in both groups were women: 53.9 percent of those who underwent simultaneous surgery and 61.3 percent of those who underwent two procedures.
In this study, patients who underwent simultaneous knee replacements had:
higher risk of heart attack and pulmonary embolism;
similar risk of death and stroke; and
lower risk of major joint infection or major mechanical malfunction.
"Our study found that the risk of developing a serious joint infection that required an additional knee revision surgery was two times higher in patients who had staged knee replacements compared to the patients who had both knees replaced at the same time (2.2 percent after staged knee replacements and 1.2 percent after bilateral knee replacements)," said John P. Meehan, MD, study author and orthopaedic surgeon from the University of California, Davis.
Revision knee surgeries for problems unrelated to infection were also more common using the staged approach.
"These findings indicate that performing simultaneous knee replacements would significantly reduce the incidence of major orthopedic complications, and at the same time reduce the number of hospitalizations and the number of operating room sessions," he added.
Similar to previous studies, this study found that the risk of adverse cardiovascular events such as having a heart attack or developing a blood clot that travels to the lungs was higher after undergoing simultaneous knee replacements, but there was no significant difference in overall mortality.
Dr. Meehan added that further research is now needed to better define which patients should not be considered for bilateral simultaneous knee replacement.
Disclosures: Dr. Meehan has nothing to disclose in relation to this study.
Lauren Pearson | EurekAlert!
Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University
ASU scientists develop new, rapid pipeline for antimicrobials
14.12.2017 | Arizona State University
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
14.12.2017 | Health and Medicine
14.12.2017 | Physics and Astronomy
14.12.2017 | Life Sciences