Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

SNM 2010 Image of the Year: Molecular Imaging Shows Parathyroid Disease in Greater Detail

16.06.2010
Research shows that molecular imaging fusion with high resolution CT anatomy may result in more precise localization of parathyroid lesions

SNM’s 2010 Image of the Year illustrates the potential of hybrid molecular imaging to provide precise information about the location and function of a condition known as “hyperparathyroidism.” Researchers selected this image from more than 1,500 studies presented over the course of four days during SNM’s 57th Annual Meeting in Salt Lake City.


“Each year, SNM chooses an image that exemplifies the most cutting-edge molecular imaging research today, as well as illustrates the potential of molecular imaging to provide physicians with a critical component for the detection and diagnosis of disease,” said Michael M. Graham, Ph.D., M.D., immediate past-president of SNM. “This year’s Image of the Year provides an example of a novel imaging presentation, using a combination of single photon emission computed tomography (SPECT) with high resolution CT angiography, which pinpoints the abnormally functioning parathyroid adenoma and the arteries feeding it. With this information, physicians may be able determine the exact location and size of the abnormal gland and plan minimally invasive surgery that reduces operative time, thus improving patient care.”

The SNM Image of the Year shows the potential of fusion of high-resolution 3D anatomy with functional SPECT images to provide critical information to help physicians to diagnose and treat hyperparathyroidism, an endocrine disease that occurs when the parathyroid glands develop a small adenoma, a benign tumor that produces too much hormone and causes high levels of calcium in the blood. It is usually treated by invasive, exploratory surgery. Using fusion images, physicians can obtain detailed information about the anatomical localization, blood supply and metabolism of the overactive parathyroid adenoma.

In this study, researchers scanned 31 patients with symptoms of primary hyperparathyroidism using a nuclear medicine technique called MIBI, combined with SPECT and multidetector computed tomography (MDCT). Researchers obtained thin-slice multiplanar reconstruction images of the neck using a 64-row MDCT with contrast enhancement. When the enlarged gland was successfully identified, volume-rendered images of the thyroid and parathyroid with feeding arteries were generated. Then, 2- and 3-dimensional fusion images were also obtained using dedicated workstations. The diagnostic value of 3-dimensional SPECT/CT fusion images was compared with those by MIBI SPECT alone and by ultrasound. The study shows that the hybrid molecular imaging technique was more effective than single modality scanning alone.

A total of 34 glands were identified by surgery. SPECT/CT fusion image, MIBI SPECT and ultrasound identified 32 (94%), 27 (79%) and 27 (79%) adenomas, respectively. The fusion imaging technique identified five glands that were missed by ultrasound and MIBI SPECT. The fusion images successfully showed feeding arteries in 29 adenomas. With the use of fusion images for navigation, preliminary results in eight patients showed that operation time is decreased by approximately 82% compared to studies performed without fusion images.

According to the National Institutes of Health, approximately 100,000 Americans develop hyperparathyroidism each year. Women outnumber men two to one, and risk increases with age. In women 60 years and older, two out of 1,000 will develop hyperparathyroidism each year.

Abstract 200: K. Nakada, I. Sakuma, M. Sakurai, K. Noriyasu, Hokko Memorial Hospital, Sapporo, Japan; N. Takada, Kaisei Hospital, Sapporo, Japan; H. Takahashi, Hokkaido University Hospital, Sapporo, Japan. “Clinical Value of Fusion Images of MIBI SPECT and Enhanced MDCT Registered by Workstation in Primary Hyperparathyroidism.” SNM’s 57th Annual Meeting, June 5–9, 2010, Salt Lake City, Utah.

About SNM—Advancing Molecular Imaging and Therapy
SNM is an international scientific and medical organization dedicated to raising public awareness about what molecular imaging is and how it can help provide patients with the best health care possible. SNM members specialize in molecular imaging, a vital element of today’s medical practice that adds an additional dimension to diagnosis, changing the way common and devastating diseases are understood and treated.

SNM’s more than 17,000 members set the standard for molecular imaging and nuclear medicine practice by creating guidelines, sharing information through journals and meetings and leading advocacy on key issues that affect molecular imaging and therapy research and practice. For more information, visit http://www.snm.org.

Amy Shaw | EurekAlert!
Further information:
http://www.snm.org

More articles from Medical Engineering:

nachricht Surgery involving ultrasound energy found to treat high blood pressure
24.05.2018 | Queen Mary University of London

nachricht XXL computed tomography: a new dimension in X-ray analysis
17.05.2018 | Fraunhofer-Gesellschaft

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>