A potentially fatal bacterial disease of the heart, infective endocarditis frequently affects the heart's tricuspid valve, often resulting in permanent tissue damage.
But a reconstructive technique, in which the valve is repaired with a bioscaffold on which new tissue can grow, can give some patients a new lease on life—a lease that has been extended to patients at Temple University Hospital, in Philadelphia, thanks to the pioneering work of T. Sloane Guy, MD, MBA, Associate Professor of Surgery, Section Chief of Cardiovascular Surgery, and Chief of Robotics at Temple University School of Medicine (TUSM).
Dr. Guy is one of only about a dozen cardiovascular surgeons in the United States who has performed complete tricuspid valve repair procedures using CorMatrix®, an extracellular matrix (ECM) material. In 2013, he became one of the first to perform the reconstruction endoscopically using robotic techniques. He delivered a video presentation of the pioneering procedure on January 27th at the 50th annual meeting of the Society of Thoracic Surgeons (STS), held in Orlando, Florida.
Robotic surgery is a groundbreaking tool in medicine that has been both celebrated for its benefits and criticized for its high cost and high-profile failures. But according to Dr. Guy, totally endoscopic robotic heart surgery not only minimizes the size of incisions made in the chest but also takes advantage of the ability of surgeons, using robotic-assisted tools and techniques, to make high-precision, minute movements, which gives it an edge over traditional techniques.
Recently, Dr. Guy performed a robotic repair by first removing nearly all of the damaged valve from the patient's heart. He then used what he calls the 'cylinder technique' to repair the damaged tissue with a sheet of bioscaffolding that had been fashioned into a tube. The tube effectively served as a new valve.
"We used a CorMatrix® bioscaffold to completely reconstruct the valve," Dr. Guy explained. CorMatrix® bioscaffolds consist of a sheet of ECM, an acellular meshwork of fibers and carbohydrate polymers that facilitates reconstruction by giving patients' own cells a framework on which to build new tissue. Because ECM is made of natural materials, it is eventually replaced by the patient's own cells and absorbed by the body. It also has a low likelihood of rejection, since it does not contain foreign cells or proteins that could precipitate an immune response.
"Temple Cardiovascular Surgery has had a big presence at the meeting this year," Dr. Guy said.
Coauthors on the abstract included Abul Kashem, MD, Akira Shiose, MD, Thomas Kelley, James McCarthy, Richard J. Kang, Larry Kaiser, MD, and Yoshiya Toyoda, MD, from the Division of Cardiovascular Surgery at TUSM and Sheela Pai, MD, and Yanfu Shao, MD, from the Department of Anesthesiology at TUSM.
About Temple Health
Temple Health refers to the health, education and research activities carried out by the affiliates of Temple University Health System and by Temple University School of Medicine.
Temple University Health System (TUHS) is a $1.4 billion academic health system dedicated to providing access to quality patient care and supporting excellence in medical education and research. The Health System consists of Temple University Hospital (TUH), ranked among the "Best Hospitals" in the region by U.S. News & World Report; TUH-Episcopal Campus; TUH-Northeastern Campus; Fox Chase Cancer Center, an NCI-designated comprehensive cancer center; Jeanes Hospital, a community-based hospital offering medical, surgical and emergency services; Temple Transport Team, a ground and air-ambulance company; and Temple Physicians, Inc., a network of community-based specialty and primary-care physician practices. TUHS is affiliated with Temple University School of Medicine.
Temple University School of Medicine (TUSM), established in 1901, is one of the nation's leading medical schools. Each year, the School of Medicine educates approximately 840 medical students and 140 graduate students. Based on its level of funding from the National Institutes of Health, Temple University School of Medicine is the second-highest ranked medical school in Philadelphia and the third-highest in the Commonwealth of Pennsylvania. According to U.S. News & World Report, TUSM is among the top 10 most applied-to medical schools in the nation.
Jeremy Walter | EurekAlert!
New investigation of endovenous laser ablation of varicose veins
11.05.2016 | Kazan Federal University
A laser for your eyes
18.04.2016 | Lomonosov Moscow State University
Permanent magnets are very important for technologies of the future like electromobility and renewable energy, and rare earth elements (REE) are necessary for their manufacture. The Fraunhofer Institute for Mechanics of Materials IWM in Freiburg, Germany, has now succeeded in identifying promising approaches and materials for new permanent magnets through use of an in-house simulation process based on high-throughput screening (HTS). The team was able to improve magnetic properties this way and at the same time replaced REE with elements that are less expensive and readily available. The results were published in the online technical journal “Scientific Reports”.
The starting point for IWM researchers Wolfgang Körner, Georg Krugel, and Christian Elsässer was a neodymium-iron-nitrogen compound based on a type of...
In the Beyond EUV project, the Fraunhofer Institutes for Laser Technology ILT in Aachen and for Applied Optics and Precision Engineering IOF in Jena are developing key technologies for the manufacture of a new generation of microchips using EUV radiation at a wavelength of 6.7 nm. The resulting structures are barely thicker than single atoms, and they make it possible to produce extremely integrated circuits for such items as wearables or mind-controlled prosthetic limbs.
In 1965 Gordon Moore formulated the law that came to be named after him, which states that the complexity of integrated circuits doubles every one to two...
Characterization of high-quality material reveals important details relevant to next generation nanoelectronic devices
Quantum mechanics is the field of physics governing the behavior of things on atomic scales, where things work very differently from our everyday world.
When current comes in discrete packages: Viennese scientists unravel the quantum properties of the carbon material graphene
In 2010 the Nobel Prize in physics was awarded for the discovery of the exceptional material graphene, which consists of a single layer of carbon atoms...
The trend-forward world of display technology relies on innovative materials and novel approaches to steadily advance the visual experience, for example through higher pixel densities, better contrast, larger formats or user-friendler design. Fraunhofer ISC’s newly developed materials for optics and electronics now broaden the application potential of next generation displays. Learn about lower cost-effective wet-chemical printing procedures and the new materials at the Fraunhofer ISC booth # 1021 in North Hall D during the SID International Symposium on Information Display held from 22 to 27 May 2016 at San Francisco’s Moscone Center.
24.05.2016 | Event News
20.05.2016 | Event News
19.05.2016 | Event News
25.05.2016 | Trade Fair News
25.05.2016 | Life Sciences
25.05.2016 | Power and Electrical Engineering